ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
Which antipsychotic has the most sedative potential and is sometimes questionably used as a hypnotic agent in certain clinical settings?
Correct Answer: C
Rationale: Quetiapine, a second-generation antipsychotic, has strong histamine H1 antagonism, conferring potent sedation, especially at low doses. This property leads to off-label use as a hypnotic in insomnia, though controversial due to metabolic risks. Fluphenazine and haloperidol, high-potency first-generation drugs, lack sedation, focusing on D2 blockade. Thiothixene, mid-potency, has minimal sedative effects. Iloperidone is less sedating. Quetiapine's antihistaminic action, backed by clinical practice, makes it the most sedative antipsychotic, often leveraged for sleep despite primary indications.
Question 2 of 5
Which assessment finding, by the nurse, is a priority concern when a client receives pseudoephedrine (Sudafed)?
Correct Answer: C
Rationale: In this scenario, the correct answer is option C) Heart rate 82 and irregular. When a client receives pseudoephedrine, a sympathomimetic medication, monitoring the heart rate is crucial because pseudoephedrine can cause cardiovascular side effects like tachycardia and irregular heart rhythms. These effects can be serious and potentially life-threatening, hence making it a priority concern for the nurse. Option A) Temperature of 100°F is not directly related to the administration of pseudoephedrine and is less concerning compared to potential cardiac complications. Option B) Respiratory rate of 22 is within normal limits and not a common side effect of pseudoephedrine. Option D) Complaints of a dry mouth are a common side effect of pseudoephedrine but not as critical as monitoring for cardiovascular issues. Educationally, understanding the potential side effects of medications and knowing which assessments are a priority based on the pharmacological action of the drug is essential for nursing practice. This question highlights the importance of monitoring vital signs and recognizing priority concerns when administering medications that can have significant physiological effects on the body.
Question 3 of 5
The nurse is caring for a client receiving isoniazid (INH) for tuberculosis. Which instruction should the nurse include?
Correct Answer: C
Rationale: Isoniazid treats TB but risks hepatotoxicity, causing jaundice (yellowing skin, choice C), a serious sign needing immediate reporting to prevent liver failure. Food is optional'INH can be taken either way. Tyramine relates to MAOIs, not INH. Bedtime isn't specific'dosing is flexible. Reporting jaundice aligns with INH's side effect profile, critical in TB therapy where long-term use is common, making C the essential instruction for early detection and safety.
Question 4 of 5
The pharmacokinetic elimination half-life of the following drugs mirrors their pharmacodynamic duration and intensity of action:
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Selegiline:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.