ATI RN
ATI Pharmacology Made Easy 4.0 Infection Questions
Question 1 of 5
Which antipsychotic agent has been most associated with significant QT interval prolongation and should be used with caution in patients with preexisting arrhythmias or patients taking other drugs associated with QT prolongation?
Correct Answer: A
Rationale: Thioridazine, a first-generation antipsychotic, potently blocks potassium channels, prolonging QT intervals and risking torsades de pointes, especially in patients with arrhythmias or on QT-prolonging drugs. This led to restricted use. Risperidone, asenapine, and lurasidone, second-generation agents, have milder QT effects. Aripiprazole is minimal. Thioridazine's strong association, evidenced by black box warnings, demands caution, making it the standout risk here.
Question 2 of 5
The nurse teaches the client about the difference between oral and nasal decongestants. The nurse evaluates that learning has been effective when the client makes which statement?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
The nurse is caring for a client receiving amphotericin B for a fungal infection. Which adverse effect should the nurse monitor closely?
Correct Answer: A
Rationale: Amphotericin B, an antifungal, is nephrotoxic , damaging renal tubules and reducing GFR, a severe effect needing close monitoring (e.g., creatinine, urine output) to adjust dosing or hydration. Ototoxicity , hepatotoxicity , and cardiotoxicity are less common. Nephrotoxicity's frequency and severity align with amphotericin's membrane-binding mechanism, critical in fungal infections where prolonged use is typical, making A the priority to monitor for renal protection.
Question 4 of 5
The following drugs have an elimination half-life of less than 4 hours in a healthy adult:
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
Pethidine:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.