Which action is most important for the nurse to teach a patient who is taking tositumomab?

Correct Answer: C

Rationale: Tositumomab is a radioactive monoclonal antibody used in cancer treatment. Patients should be advised to use a separate bathroom and sit while urinating to minimize radiation exposure to others and themselves. This precaution is necessary because the drug is excreted in urine, which remains radioactive for a period after treatment. Avoiding alcohol or smoking is not specifically related to tositumomab therapy. Taking the drug on an empty stomach is not applicable, as it is administered intravenously.

Correct Answer: A

Rationale: Varenicline, a nicotinic receptor partial agonist, aids smoking cessation. Abnormal dreams are common, reflecting CNS effects. Gastric ulcers , pancreatitis , photosensitivity , and seizures (E) are rare. Dreams align with its neuropsychiatric profile, a key counseling point.

Correct Answer: D

Rationale: Packed red blood cells (PRBCs) always require cross-matching to ensure compatibility between the donor and recipient blood types. Cross-matching involves testing the recipient's serum against the donor's red cells to detect antibodies that could cause a transfusion reaction. Granulocytes, platelets, and plasma do not require cross-matching in the same way, although they may undergo other compatibility tests. PRBCs are the most critical to match correctly due to the risk of hemolytic reactions, which can be life-threatening.

Correct Answer: B

Rationale: Warfarin is an anticoagulant medication that works by inhibiting the body's ability to use vitamin K to form clotting factors. In cases of excessive anticoagulation or bleeding due to Warfarin, the antidote is vitamin K. Vitamin K helps the body produce clotting factors, thereby reversing the effects of Warfarin and promoting the blood to clot normally. Other medications like Narcan, Glucagon, and Vitamin B do not have a direct antidote effect for Warfarin toxicity.

Correct Answer: A

Rationale: Long half-life drugs (e.g., diazepam) linger, risking fetal exposure post-conception, a pharmacokinetic worry for serious conditions. No active metabolites reduce risk. High protein-binding limits free drug, less concern. As-needed use minimizes exposure. Long half-life heightens teratogenic potential, critical in planning.