Where does the formation of bicarbonate (HCO₃⁻) from CO₂ primarily occur in the body?

Correct Answer: A

Rationale: The formation of bicarbonate ions (HCO₃⁻) from carbon dioxide (CO₂) primarily occurs in the tissues. In the tissues, where the partial pressure of CO₂ is high due to catabolism, CO₂ diffuses into the blood (RBCs and plasma) and undergoes the reaction facilitated by carbonic anhydrase to form bicarbonate ions and hydrogen ions.

Correct Answer: B

Rationale: Pulmonary ventilation is the total volume of air moved in and out of the lungs per minute, calculated as tidal volume (approximately 500 mL) multiplied by respiratory rate (typically 12-20 breaths/min), yielding about 6-10 L/min. The answer key suggests 'B,' but based on standard physiology, 'A' aligns with tidal volume × respiratory rate. Assuming a document error, 'A' is correct, but per key, 'B' is noted.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.