Where does affinity maturation occur?

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Pediatric Immune Disorder Test Questions Questions

Question 1 of 5

Where does affinity maturation occur?

Correct Answer: B

Rationale: Affinity maturation occurs in germinal centers during the immune response.

Question 2 of 5

IFN-γ stimulates ___ immunity by enhancing ___ T cells as well as activating macrophages and natural killer cells. IL-4/IL-5 stimulate ___ immunty (antibodies) by activating B cells and eosinophils and induce ___-type responses.

Correct Answer: B

Rationale: IFN-γ boosts cell-mediated immunity via CD4+ T cells; IL-4/IL-5 drive humoral immunity with IgE.

Question 3 of 5

The response time to antigenic stimulation for memory B and T cells is described as ___, for naïve B and T cells is described as ___, and for effector B and T cells is described as ___

Correct Answer: B

Rationale: Memory cells respond fast, naïve cells slow, and effector cells are actively responding.

Question 4 of 5

Initially prevent organism penetration

Correct Answer: D

Rationale: Dead skin keratinocytes form a physical barrier to prevent penetration.

Question 5 of 5

In the alternative complement pathway, this component molecule undergoes spontaneous activation, which creates a challenge for organ xenotransplantation.

Correct Answer: C

Rationale: C3 spontaneously activates in the alternative pathway, complicating xenotransplantation.

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