When teaching a patient about antihypertensive drug therapy, which statements by the nurse are correct? (Select all that apply.)

Correct Answer: A

Rationale: A. You need to have your blood pressure checked once a week and keep track of the readings. - This is correct because monitoring blood pressure regularly is essential to assess the effectiveness of antihypertensive drug therapy and make any necessary adjustments.

Correct Answer: B

Rationale: Epinephrine can compromise the stability of a formed blood clot because it is a fibrinolytic agent. Fibrinolysis is the process of breaking down fibrin, the main protein component of blood clots, and promoting the dissolution of the clot. Epinephrine is a hormone that acts on adrenergic receptors, including beta-2 adrenergic receptors, which can trigger the activation of fibrinolysis pathways. By promoting fibrinolysis, epinephrine can weaken and compromise the stability of a formed blood clot, leading to potential clot breakdown and increased risk of bleeding. This mechanism is important to consider when using epinephrine in situations where clot stability is crucial, such as in patients with bleeding disorders or undergoing surgery.

Correct Answer: D

Rationale: Amiodarone inhibits warfarin metabolism, increasing INR, so it affects anticoagulation. Disulfiram also potentiates warfarin via CYP inhibition, enhancing effect. Fluconazole similarly boosts warfarin levels, a significant interaction. Benzodiazepines have no major effect on anticoagulant therapy, a true statement, as they're metabolized differently. Metronidazole, like fluconazole, increases warfarin effect. Benzodiazepines' lack of interaction makes them safer in this context, a key consideration in polypharmacy.

Correct Answer: C

Rationale: Naloxone is a medication used to reverse the effects of an opioid overdose. It works by binding to the opioid receptors in the brain, displacing the opioids and temporarily reversing their effects. Naloxone is commonly administered in emergency situations to quickly restore normal breathing and consciousness in individuals who have overdosed on opioids. Aspirin (choice A) and Advil (choice B) are non-opioid pain relievers and do not reverse the effects of an opioid overdose. Ondansetron (choice D) is an anti-nausea medication and does not counteract the respiratory depression caused by opioid overdose.

Correct Answer: A

Rationale: TPN tubing should be changed every 24 hours to prevent infection and maintain sterility. Longer intervals (B, C, D) increase the risk of bacterial contamination and sepsis.