Correct Answer: B

Rationale: It is crucial to rotate the application site daily when using nitroglycerin patches to prevent skin irritation and ensure optimal absorption of the medication.

Correct Answer: C

Rationale: Lithium is primarily used to stabilize mood, especially in conditions like bipolar disorder. It helps in reducing the frequency and severity of manic episodes, making it an essential medication for mood stabilization.

Correct Answer: A

Rationale: Weight gain is a common adverse effect of long-term prednisone use.

Correct Answer: A

Rationale: Spironolactone is classified as a potassium-sparing diuretic. It works by inhibiting sodium reabsorption in the kidneys while promoting the retention of potassium and hydrogen ions. This mechanism of action helps in reducing fluid retention without causing excessive loss of potassium, which is a common side effect of other diuretics.

Correct Answer: A

Rationale: Acetaminophen is known to lose its effectiveness in controlling pain beyond a dosage of 1,000 mg. It is important to adhere to recommended dosages to ensure optimal pain relief and avoid potential adverse effects associated with higher doses.