ATI RN
ATI Pharmacology Practice A Questions
Question 1 of 5
When taking Nitroglycerine (transdermal), you should have how many hours nitrate free each day?
Correct Answer: D
Rationale: When using Nitroglycerine transdermal patches, it is recommended to have a nitrate-free period of at least 10-12 hours each day to prevent the development of tolerance to the medication. Continuous exposure to nitrates can lead to a decrease in efficacy over time. By having a nitrate-free interval each day, the body has a chance to "reset" and maintain the effectiveness of the medication for angina control. It is crucial to follow this dosing schedule as directed by a healthcare provider to ensure optimal benefits and reduce the risk of tolerance.
Question 2 of 5
What is the most important patient/family teaching for patients that are taking Digoxin
Correct Answer: D
Rationale: The most important patient teaching for patients taking Digoxin is to regularly monitor and take their pulse. Digoxin is a medication used to treat certain heart conditions by helping the heart beat stronger and more regularly. Monitoring the pulse is important because Digoxin can affect the heart rate, and if the pulse is too slow or irregular, it may indicate an adverse reaction to the medication. Patients should be taught how to check their pulse and to contact their healthcare provider if they notice any significant changes in their heart rate while taking Digoxin. Taking the pulse is crucial in ensuring the medication is being tolerated well and is working effectively.
Question 3 of 5
Group of drugs which acts on amixed group of receptors:
Correct Answer: A
Rationale: Mixed agonist-antagonist drugs exhibit both agonistic and antagonistic properties at different receptor sites. These drugs can act as agonists at certain receptors while acting as antagonists at other receptors. This classification of drugs is distinct from pure agonists, pure antagonists, or partial agonists, as mixed agonist-antagonist drugs have a more complex mechanism of action. An example of a mixed agonist-antagonist drug is buprenorphine, which acts as a partial agonist at the mu opioid receptor and an antagonist at the kappa opioid receptor.
Question 4 of 5
Of the following salicylates, which does not exhibit an analgesic effects:
Correct Answer: C
Rationale: Salicylic acid, which is the parent compound of the salicylate drug class, does not exhibit analgesic effects. In order to have analgesic effects, such as pain relief, salicylic acid needs to be modified into derivatives like acetyl salicylic acid (aspirin), sodium salicylate, salicylamide, and diflunisal. These derivatives possess analgesic, antipyretic, and anti-inflammatory properties due to their ability to inhibit cyclooxygenase enzymes (COX) and subsequently decrease prostaglandin production.
Question 5 of 5
The nurse is performing a health history on a patient who is ordered to begin therapy with valproic
Correct Answer: D
Rationale: Valproic acid is known to have potential hepatotoxicity, meaning it can damage the liver. Therefore, if a patient already has liver disease, it can increase the risk of further liver damage when taking valproic acid. The nurse needs to be particularly cautious when a patient with pre-existing liver disease is prescribed this medication, as close monitoring of liver function tests will be necessary to detect any signs of liver damage early on. It is important to assess and consider the patient's liver condition before initiating valproic acid therapy to prevent potential adverse effects.