ATI RN
Immune System NCLEX Questions Quizlet Questions
Question 1 of 5
When macrophages in a tissue encounter bacteria, they release cytokines that induce an inflammatory response. These cytokines act on other immune cells, to recruit them to the site of infection and to enhance their activities. In addition, these cytokines act on the endothelial cells of the blood vessel wall to:
Correct Answer: A
Rationale: Cytokines increase endothelial permeability for immune cell extravasation; tightening junctions , proliferation , or microbicidal action aren't primary effects.
Question 2 of 5
Recombination signal sequences are conserved heptamer and nonamer sequences that flank the V, J, and D gene segments which undergo recombination to generate the final V region coding exon. Some of these have 12-nucleotide spacers between the heptamer and nonamer, and others have 23-nucleotide spacers. The reason recombination signal sequences come in these two forms is:
Correct Answer: A
Rationale: 12/23 rule ensures V-D-J assembly ; not helix face , locus specificity , or non-Ig genes .
Question 3 of 5
The reason for naming the closed circulatory systems
Correct Answer: C
Rationale: Closed circulatory systems are named so because blood remains confined within vessels, unlike open systems where it bathes tissues directly.
Question 4 of 5
One kind of vaccine consists of
Correct Answer: C
Rationale: Vaccines often use weakened or inactivated pathogens to stimulate immunity, not antibodies, B cells, or antibiotics.
Question 5 of 5
Which of the following statements about HIV is false?
Correct Answer: B
Rationale: HIV targets helper T cells, not mast cells (involved in allergies), making B false; others are true.