ATI RN
Mastering Microbiology Test Bank Questions
Question 1 of 9
When examining a patient presumptively diagnosed with food toxicoinfection, a doctor on duty has detected symptoms characteristic of botulism. The patient named the meals he ate the day before. What is the most probable cause of infection?
Correct Answer: A
Rationale: The correct answer is A: Homemade canned meat. Botulism is caused by the Clostridium botulinum bacteria, which thrives in low-oxygen environments like improperly canned food. Homemade canned meat poses a higher risk of contamination as it may not have been processed correctly, allowing the bacteria to grow and produce toxins. Custard pastry, sour cream, and strawberries are less likely to cause botulism as they are not typically associated with the bacteria unless improperly handled or stored. Homemade canned meat is the most probable cause based on the characteristic symptoms of botulism and the conditions that favor the growth of Clostridium botulinum in canned food.
Question 2 of 9
A patient with a deep tissue infection had a wound culture revealing Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-negative. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus epidermidis. The presence of Gram-positive cocci in clusters that are catalase-positive and coagulase-negative points towards coagulase-negative staphylococci like Staphylococcus epidermidis. Staphylococcus aureus is catalase-positive and coagulase-positive. Streptococcus pyogenes is catalase-negative. Enterococcus faecalis is catalase-negative and not typically seen in clusters. Therefore, the most likely causative agent in this scenario is Staphylococcus epidermidis.
Question 3 of 9
The main function of bacterial ribosomes is:
Correct Answer: B
Rationale: The correct answer is B: protein synthesis. Bacterial ribosomes are responsible for translating messenger RNA into proteins through a process called translation. Ribosomes are composed of both protein and RNA molecules and facilitate the binding of transfer RNA to the messenger RNA to assemble the amino acids in the correct order to form a protein. DNA replication (A) is carried out by enzymes such as DNA polymerase, not ribosomes. Cell wall synthesis (C) is a process involving enzymes that build the structure of the cell wall in bacteria. RNA splicing (D) is a eukaryotic process that involves removing introns from pre-mRNA molecules, which is not a function of bacterial ribosomes.
Question 4 of 9
One of the basic principles of chemotherapy is:
Correct Answer: A
Rationale: The correct answer is A: Selective toxicity. Chemotherapy aims to target cancer cells while minimizing harm to healthy cells, known as selective toxicity. This principle is crucial to effectively treat cancer without causing excessive damage to the patient's body. Accumulation in the macroorganism (B) and causing allergies (C) are not fundamental principles of chemotherapy and can lead to harmful side effects. Therefore, the correct answer is A as it aligns with the core objective of chemotherapy.
Question 5 of 9
Precipitation reaction can be converted into agglutination reaction by coating soluble antigen onto
Correct Answer: D
Rationale: The correct answer is D: All of these. Coating soluble antigen onto Bentonite particles, RBCs, or Latex particles can convert a precipitation reaction into an agglutination reaction. This is because soluble antigens bind to their specific antibodies, causing the particles to clump together, visible as agglutination. Bentonite particles, RBCs, and Latex particles all provide surfaces for the antigen-antibody interaction to occur, leading to agglutination. Therefore, all of these options are correct for converting precipitation reactions to agglutination reactions.
Question 6 of 9
The main structure components of viruses are
Correct Answer: A
Rationale: The correct answer is A: nucleic acid and proteins. Viruses consist of genetic material (nucleic acid) surrounded by a protein coat. The nucleic acid carries the viral genetic information, while the proteins form the capsid that protects the genetic material. This combination is essential for the virus to infect host cells and replicate. Lipids (choice B) are not typically part of the main structure of viruses. Lipids are more commonly found in the host cell membrane. Lipids and proteins (choice C) may be present in the viral envelope but are not the main structural components. Proteins and glycoproteins (choice D) are important for viral attachment and entry into host cells but do not constitute the main structural components of viruses.
Question 7 of 9
On the 5th day after a surgery for colon injury a patient complains of bursting pain in the postoperative wound, weakness, drowsiness, headache, fever up to 40oC. Objectively: the skin around the wound is swollen, there is gas crepitation. The wound discharges are scarce foul-smelling, of dark-gray color. What is the most likely diagnosis?
Correct Answer: A
Rationale: The correct answer is A: Anaerobic clostridial wound infection. The symptoms and signs described (bursting pain, weakness, drowsiness, fever, swollen skin, gas crepitation, foul-smelling dark-gray discharge) are classic for gas gangrene, caused by Clostridium perfringens. Gas gangrene is an anaerobic infection that thrives in devitalized tissue, such as postoperative wounds. The gas crepitation is due to gas production by the bacteria. Abscess (B) typically presents with localized swelling and fluctuance, not gas crepitation. Postoperative wound infection (C) may present with redness, warmth, and increased wound discharge but not the specific features mentioned. Erysipelas (D) is a superficial bacterial skin infection, typically caused by Streptococcus pyogenes, presenting with well-defined raised borders and redness.
Question 8 of 9
All of the following areas of the human body contain normal flora except:
Correct Answer: A
Rationale: The correct answer is A: Peritoneum. Normal flora refers to the microorganisms that naturally inhabit the human body without causing harm. The peritoneum is a sterile area, so it does not harbor normal flora. The urethra, vagina, and mouth all have normal flora due to their moist and warm environments, which provide an ideal habitat for microorganisms to thrive. The peritoneum, being a sterile cavity that houses organs like the stomach and intestines, does not have a natural microbial population like the other areas mentioned. Therefore, it does not contain normal flora.
Question 9 of 9
A patient of surgical department complains about pain in the small of her back and in the lower part of her belly; painful and frequent urination. Bacteriological examination of urine revealed gram-negative oxidase-positive rod-like bacteria forming greenish mucoid colonies with specific smell. What causative agent can it be?
Correct Answer: B
Rationale: The correct answer is B: Proteus mirabilis. This bacterium is known to cause urinary tract infections (UTIs) and matches the description given in the question. Proteus mirabilis is a gram-negative rod-like bacterium that forms greenish mucoid colonies with a specific smell due to its production of urease enzyme. This enzyme leads to the formation of struvite crystals, which can cause painful and frequent urination. Pseudomonas aeruginosa (A) is not typically associated with UTIs. E.coli (C) is the most common cause of UTIs but does not match the specific description provided. Str.pyogenes (D) is a gram-positive bacterium and is not typically associated with UTIs.