ATI RN
Principles of Pharmacology Quizlet Questions
Question 1 of 5
When considering the dosage requirement for a 6-feet (1.8-m) tall client who weighs 280 pounds (127 kg), which statement is accurate?
Correct Answer: A
Rationale: The correct answer is A. For a 6-feet tall client weighing 280 pounds, the dose will be higher due to increased body weight requiring higher medication levels for therapeutic effect. Body weight influences drug distribution and metabolism. Option B is incorrect as higher weight typically requires higher dosage. Option C is incorrect as weight affects drug dosage. Option D is unrelated to the question about dosage based on weight and height.
Question 2 of 5
A client tells the nurse, “I took my sleeping pill yesterday evening, but it didn’t seem to work for me like it usually does.” The nurse should consider which variable that can affect drug absorption? Select all that apply.
Correct Answer: A
Rationale: The correct answer is A: GI function. The absorption of drugs can be affected by the gastrointestinal (GI) function, including factors like gastric emptying time, pH of the stomach, and presence of food or other substances in the digestive tract. These factors can impact how quickly and effectively a drug is absorbed into the bloodstream. In this case, if the client's GI function is altered, it could explain why the sleeping pill did not work as expected. Summary of other choices: B: Blood flow to the site of administration - While blood flow can affect the distribution of a drug in the body, it does not directly impact drug absorption. C: The presence of other drugs - While interactions between drugs can affect drug efficacy, this primarily affects metabolism and excretion, not absorption. D: Route of administration - The route of administration affects how a drug is delivered to the body, but it does not directly impact drug absorption in this scenario.
Question 3 of 5
A client with cancer is taking the prescribed dose of morphine sulfate, and a family member informs the nurse that the client is extremely sedated. What finding by the nurse would indicate the causative factor for the increased sedation experienced by the client?
Correct Answer: A
Rationale: The correct answer is A: The client is taking St. John’s wort for depression. St. John’s wort is known to interact with morphine sulfate, potentiating its sedative effects due to its impact on liver enzymes. This interaction can lead to increased sedation in the client. Incorrect choices: B: The client has a glass of ginger ale by the bedside. Ginger ale does not interact with morphine sulfate to cause increased sedation. C: A family member has a naloxone pen by the bedside. Naloxone is an opioid antagonist used to reverse opioid overdose, not a causative factor for increased sedation. D: The client is taking metoprolol for hypertension. Metoprolol is a beta-blocker and does not interact with morphine sulfate to cause increased sedation.
Question 4 of 5
The route of excretion of a volatile drug will likely be:
Correct Answer: B
Rationale: The correct answer is B: The lungs. Volatile drugs are typically eliminated through exhalation via the lungs due to their ability to evaporate easily into the air. This route is favored for volatile drugs as they can be quickly eliminated through respiration, making it an efficient and rapid process. A: The kidneys primarily excrete water-soluble compounds through urine, not volatile drugs. C: The bile and feces are involved in the excretion of non-volatile, lipophilic drugs, but not volatile drugs. D: The skin is not a primary route of excretion for drugs, especially volatile ones.
Question 5 of 5
Azithromycin dosing requires the first day’s dose be twice those of the other 4 days of the prescription. This is considered a loading dose. A loading dose:
Correct Answer: A
Rationale: The correct answer is A because a loading dose allows for a rapid achievement of drug levels in the therapeutic range on the first day. By administering a higher initial dose, the drug concentration quickly reaches the desired level. Choice B is incorrect because a loading dose does not necessarily require multiple half-lives to attain. Choice C is incorrect as renal function typically influences maintenance doses rather than loading doses. Choice D is incorrect because a loading dose is primarily focused on achieving therapeutic levels in the bloodstream, not specifically targeting tissues.