ATI RN
ATI Pharmacology Book Questions
Question 1 of 5
When collecting a medication history from a patient with primary open-angle glaucoma, the nurse identifies several drugs that could exacerbate glaucoma. Which drug poses a priority concern for this particular patient?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
The nurse is aware that the following solutions are routinely used to flush an IV device before and after the administration of blood to a patient is:
Correct Answer: A
Rationale: 0.9 percent sodium chloride (normal saline) is the standard solution used to flush IV devices before and after blood transfusions. It is isotonic and compatible with blood products, preventing hemolysis or clotting. Dextrose solutions and sterile water are not used because they can cause hemolysis of red blood cells. Heparin sodium is used for maintaining patency in certain IV lines but is not suitable for blood transfusions. Therefore, normal saline is the correct choice for flushing IV devices in this context.
Question 3 of 5
Which of the following drugs is more likely to cause hyperkalaemia than hypokalaemia in a patient with diabetes and estimated glomerular filtration rate (eGFR) within the 'normal' reference range?
Correct Answer: D
Rationale: Hyperkalemia involves elevated potassium, hypokalemia reduced levels. Amphotericin causes hypokalemia via renal potassium wasting, not hyperkalemia. Prednisolone, a glucocorticoid, promotes potassium excretion, risking hypokalemia. Low molecular weight heparin (LMWH) rarely affects potassium directly with normal eGFR. Salmeterol, a beta-agonist, can shift potassium intracellularly, causing hypokalemia. Insulin, in diabetes management, drives potassium into cells with glucose, potentially causing hyperkalemia if renal excretion is impaired, though less common with normal eGFR. However, its potassium-shifting effect makes hyperkalemia more likely than hypokalemia compared to others, especially in acute settings, a key consideration in diabetic care.
Question 4 of 5
Tricyclic antidepressants:
Correct Answer: C
Rationale: Tricyclic antidepressants (TCAs) like amitriptyline have a high volume of distribution due to lipophilicity, not low, making that false. They're not useful in urinary retention (they cause it as a side effect) but are effective for chronic pain via monoamine modulation, so that's partially false. They can prolong the QT interval by blocking cardiac sodium channels, a true statement and significant risk factor for arrhythmias. They don't block monoamine oxidase (MAO) but inhibit reuptake of norepinephrine and serotonin, increasing synaptic levels, so that's false. They treat severe depression, even with suicidal ideation, though caution is needed. The QT prolongation is a critical electrophysiological effect, requiring ECG monitoring in clinical use to prevent torsades de pointes.
Question 5 of 5
A male client has erectile dysfunction. Which systems should be assessed that could contribute to the erectile dysfunction?
Correct Answer: A
Rationale: Erectile dysfunction (ED) often stems from cardiovascular issues, like atherosclerosis or hypertension, which impair blood flow to the penis, a vascular process essential for erection. The integumentary system, while relevant to skin health, doesn't directly influence ED unless severe conditions affect genital tissue, which is rare. Endocrine disorders, such as diabetes or low testosterone, disrupt hormonal balance critical for libido and erectile function, making it a key area. The nervous system, including spinal cord injuries or neuropathy, affects nerve signals for arousal, another vital component. Cardiovascular assessment is prioritized because ED can signal underlying heart disease, with shared risk factors like smoking or high cholesterol, and its vascular basis often precedes overt cardiac symptoms, necessitating a thorough check of circulation and heart health to pinpoint or rule out this common cause.