ATI RN
ATI Intro to Pharmacology Quizlet Questions
Question 1 of 5
When administering the anticoagulant drug Warfarin, what is one of the two lab tests you should monitor to distinguish the effectiveness of the drug?
Correct Answer: B
Rationale: When administering the anticoagulant drug Warfarin, one of the two lab tests you should monitor to distinguish the effectiveness of the drug is the International Normalized Ratio (INR). INR measures the time it takes for blood to clot and is used to monitor the effects of Warfarin therapy. The target INR range for patients on Warfarin therapy varies depending on the indication for treatment, but in general, a higher INR indicates that the blood is taking longer to clot, which means the Warfarin is working effectively to prevent blood clots. Regular monitoring of the INR levels is essential to ensure that patients are receiving an appropriate dose of Warfarin to prevent both clotting and bleeding complications.
Question 2 of 5
A patient with diabetes has a new prescription for the ACE inhibitor lisinopril. She questions this order because her physician has never told her that she has hypertension. What is the best explanation for this order?
Correct Answer: D
Rationale: The correct explanation for the prescription of the ACE inhibitor lisinopril for a patient with diabetes who does not have hypertension is that this medication has cardioprotective properties. ACE inhibitors, such as lisinopril, have been shown to have beneficial effects beyond just lowering blood pressure. They have been found to reduce the risk of cardiovascular events and complications in patients with diabetes, even in the absence of hypertension. Therefore, the prescription of lisinopril for a patient with diabetes may be for its cardioprotective properties rather than for hypertension control.
Question 3 of 5
If you are treating a patient that has renal failure, what type of pain medications should you avoid?
Correct Answer: B
Rationale: In patients with renal failure, NSAIDs (Nonsteroidal anti-inflammatory drugs) should be avoided as they can further impair kidney function and potentially cause kidney damage. NSAIDs can lead to acute kidney injury and worsen existing renal conditions by affecting prostaglandin synthesis in the kidneys, leading to decreased renal blood flow. It is essential to choose pain medications that do not rely on the kidneys for metabolism or excretion, such as nonopioid analgesics or certain types of opioids that are safe for use in renal impairment. It is advisable to consult with a healthcare provider for proper pain management in patients with renal failure.
Question 4 of 5
At a dose of 10 mg, drug X lowers total cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 65 mg/dL is achieved at 40 mg. At a dose of 5 mg, drug Y lowers cholesterol by 50 mg/dL, while a maximum drop in cholesterol of 55 mg/dL is achieved at 10 mg. What can be concluded about the efficacy and potency of these two drugs?
Correct Answer: D
Rationale: Potency is dose for effect-Drug Y lowers 50 mg/dL at 5 mg, versus X at 10 mg, making Y more potent. Efficacy is max effect-X's 65 mg/dL beats Y's 55 mg/dL, giving X higher efficacy. X isn't more potent-higher dose needed. Y's potency and X's efficacy align with data, per pharmacodynamics.
Question 5 of 5
A 48-year-old woman with obsessive-compulsive disorder presents to her primary care physician for evaluation. She states that her symptoms have worsened during the last 6 months and desires treatment. She has begun on sertraline. Which of the following precautions must be exercised by the physician?
Correct Answer: D
Rationale: Sertraline, an SSRI, risks suicidal tendencies , especially early in treatment for OCD. Hepatic carcinoma , volume overload , and antibiotic potentiation aren't concerns. FDA warnings highlight this risk, necessitating monitoring in this worsening case.