ATI RN
Virtual ATI Pharmacology Assessment Questions
Question 1 of 5
When administering Phenytoin you should monitor?
Correct Answer: D
Rationale: When administering Phenytoin, it is essential to monitor all of the above: behavior, therapeutic blood levels, and for the development of Steven Johnson syndrome.
Question 2 of 5
A 28-year-old woman presents to the emergency department in an acute asthma exacerbation. Her asthma developed in her 20s after she had recurrent upper respiratory infections. She was doing well, but she twisted her ankle yesterday and was taking aspirin to reduce the inflammation. She is diagnosed with aspirin-induced asthma. What is the most appropriate long-term treatment for her condition?
Correct Answer: D
Rationale: Aspirin-induced asthma (AIA) involves leukotriene overproduction. Zafirlukast , a leukotriene receptor blocker-prevents attacks long-term. Albuterol and Ipratropium treat acutely. Cromolyn stabilizes mast cells but is less specific. Theophylline (E) is outdated. Zafirlukast targets AIA's pathophysiology.
Question 3 of 5
A patient who has been diagnosed with social anxiety disorder will begin taking venlafaxine(Effexor). The nurse who performs a medication and dietary history will be concerned about ingestion of which substance or drug?
Correct Answer: D
Rationale: St. John's wort is an herbal supplement that can interact with many medications, including venlafaxine (Effexor). When taken together, it can decrease the effectiveness of venlafaxine by increasing its metabolism, potentially leading to reduced therapeutic effects. This interaction can also increase the risk of side effects or adverse reactions. Therefore, the nurse should be concerned about the ingestion of St. John's wort when a patient is taking venlafaxine to ensure proper medication management and effectiveness. It is important for patients to inform healthcare providers about all supplements they are taking to prevent harmful interactions.
Question 4 of 5
Advise patient to avoid taking antacids or antidiarrheals for how long after taking digoxin?
Correct Answer: C
Rationale: Antacids or antidiarrheals should be avoided for at least 4 hours after taking digoxin. These medications can interfere with the absorption of digoxin in the body, thereby reducing its effectiveness. By spacing out the administration of these medications, the risk of decreased digoxin absorption and potential impact on its therapeutic effects can be minimized. It is important for patients to follow this guidance to ensure optimal effectiveness of digoxin therapy.
Question 5 of 5
The ulcerogenic properties of aspirin is caused by the following, except
Correct Answer: B
Rationale: The ulcerogenic properties of aspirin are primarily caused by the inhibition of prostaglandin synthesis, particularly through the inhibition of the enzyme cyclooxygenase-1 (Cox-1). Prostaglandins play a crucial role in maintaining the protective mucus barrier in the stomach lining. When prostaglandin synthesis is inhibited, this protective barrier is compromised, leading to increased susceptibility to damage from the acidic gastric environment. The drug's acidity itself (Choice A), by irritating the stomach lining, can contribute to ulcer formation. Thromboxane inhibition (Choice B) is not directly related to the ulcerogenic properties of aspirin but is more associated with the drug's antiplatelet effects. Cox-1 inhibition (Choice D) is a key factor in aspirin-induced gastrointestinal injury as it disrupts the normal mucosal defense mechanisms.