ATI RN
ATI Pharmacology Practice B Questions
Question 1 of 5
When administering Phenytoin you should monitor?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
What is the action of Metformin?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
What is the maximal response a drug can produce?
Correct Answer: C
Rationale: Efficacy refers to the maximal response a drug can produce, regardless of the dose. It is a measure of how well a drug can produce its desired effect. Potency, on the other hand, refers to the amount of drug required to produce a specific effect and is not related to the maximal response. An agonist is a drug that binds to and activates a receptor. Bioavailability is the fraction of the administered dose of a drug that reaches the systemic circulation.
Question 4 of 5
The health care provider is planning to discontinue a client's beta blocker. What instruction should the nurse give the client regarding the beta blocker?
Correct Answer: C
Rationale: The correct instruction for the nurse to give the client regarding discontinuing a beta blocker is that it should NOT be abruptly stopped; the dose should be tapered down. Suddenly stopping a beta blocker can lead to rebound hypertension, angina, and even heart attack in some cases. Tapering down the dose helps the body adjust gradually and reduces the risk of adverse effects associated with abrupt discontinuation. It is important for the client to follow the healthcare provider's guidance on how to safely decrease the dose of the beta blocker.
Question 5 of 5
Which of the following is used to calculate the loading dose of a drug required to reach an initial target blood concentration
Correct Answer: D
Rationale: The loading dose of a drug required to reach an initial target blood concentration is based on the volume of distribution (Vd) of the drug. The volume of distribution represents the theoretical volume that would be necessary to contain the total amount of the administered drug at the same concentration as in the blood plasma. The loading dose is calculated by multiplying the target blood concentration by the volume of distribution of the drug. This initial dose helps to rapidly achieve the desired drug concentration in the body, especially when a drug has a long half-life or when steady-state levels need to be reached more quickly. Understanding the volume of distribution of a drug is crucial in dosage calculation to ensure therapeutic efficacy and avoid potential toxicity.