ATI RN
ATI Pharmacology Practice B 2023 Questions
Question 1 of 5
When administering a loop diuretic to a patient, it is most important for the nurse to determine if the patient is also taking which drug?
Correct Answer: D
Rationale: Loop diuretics, such as furosemide, can interact with theophylline, a medication commonly used to treat asthma or chronic obstructive pulmonary disease (COPD). When both drugs are taken together, it can lead to an increased risk of theophylline toxicity due to decreased theophylline clearance. This can result in symptoms such as nausea, vomiting, seizures, and cardiac arrhythmias. Therefore, it is crucial for the nurse to determine if the patient is taking theophylline before administering a loop diuretic to prevent potential drug interactions and adverse effects.
Question 2 of 5
The nurse acknowledges that the first-line drug for treating this client's blood pressure might be which drug?
Correct Answer: C
Rationale: ACE inhibitors are considered a first-line drug for treating hypertension in many patients. They work by inhibiting the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor, leading to vasodilation and a decrease in blood pressure. ACE inhibitors are well tolerated and have been shown to reduce the risk of cardiovascular events and mortality in patients with hypertension. Other medication classes such as diuretics, alpha blockers, and alpha/beta blockers may also be used in the management of hypertension but ACE inhibitors are often preferred as a first-line therapy due to their efficacy, safety profile, and proven outcomes in hypertension management.
Question 3 of 5
A client with benign prostatic hyperplasia is to receive finasteride (Proscar). The nurse understands that this drug works by
Correct Answer: B
Rationale: Finasteride (Proscar), a 5-alpha reductase inhibitor, reduces prostate size in benign prostatic hyperplasia (BPH) by blocking dihydrotestosterone (DHT) production, shrinking glandular tissue and easing urinary obstruction. Relaxing penile smooth muscle is the role of phosphodiesterase-5 inhibitors like sildenafil, not finasteride. It lowers DHT, not testosterone, and may even slightly increase circulating testosterone, but that's not its aim. Stimulating RNA synthesis relates to androgens' anabolic effects, not finasteride's mechanism. Shrinking the prostate is its core function, taking months to reduce symptoms, distinct from acute smooth muscle relaxation or hormonal boosts, aligning with BPH management goals.
Question 4 of 5
The nurse has taught the client with osteoporosis about how to manage the illness. Which statement by the client indicates that additional teaching is necessary?
Correct Answer: C
Rationale: Calcium at bedtime risks poor absorption-meals optimize it, per pharmacokinetics-needing correction. Alcohol avoidance, walking (weight-bearing), and milk (calcium) aid osteoporosis. Bedtime timing misstep shows gaps, per education.
Question 5 of 5
The patient tells the nurse that she is interested in the human brain and questions which parts of the brain control anxiety and insomnia. What is the best reply by the nurse?
Correct Answer: A
Rationale: The limbic system (e.g., amygdala) drives anxiety-emotional response-while the reticular activating system (RAS) regulates sleep-wake, impacting insomnia, per neuroanatomy. Frontal lobes plan, not directly control these. Thalamus relays, not initiates. Hypothalamus affects sleep but less anxiety. Limbic-RAS pairing fits, answering precisely.