ATI RN
foundations in microbiology test bank Questions
Question 1 of 9
What type of bacteria is responsible for the formation of acid in the stomach?
Correct Answer: B
Rationale: The correct answer is B: Helicobacter pylori. This bacterium is responsible for stomach acid formation by producing an enzyme called urease, which converts urea into ammonia and carbon dioxide, leading to an increase in stomach pH. Staphylococcus aureus (A) does not cause stomach acid formation. Bacillus cereus (C) and Clostridium botulinum (D) are not involved in stomach acid processes.
Question 2 of 9
A patient with a productive cough and fever had a sputum smear revealing Gram-positive cocci in clusters. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus aureus. Staphylococcus aureus is a Gram-positive cocci bacterium that forms clusters and commonly causes pneumonia with a productive cough and fever. It is frequently found in sputum smears in such cases. Streptococcus pneumoniae (B) is another common cause of pneumonia but typically appears in pairs or chains, not clusters. Neisseria meningitidis (C) is a Gram-negative diplococcus that causes meningitis, not pneumonia. Klebsiella pneumoniae (D) is a Gram-negative bacterium that can cause pneumonia but appears as Gram-negative rods, not Gram-positive cocci in clusters.
Question 3 of 9
A defined microorganism can be isolated in pure culture:
Correct Answer: C
Rationale: The correct answer is C because isolating a defined microorganism in pure culture involves obtaining a single, distinct colony on solid media. This ensures that only one type of microorganism is present in the culture, preventing contamination. Liquid media can harbor multiple organisms, making it challenging to isolate a specific microorganism. Therefore, choice A is incorrect. Choice B is also incorrect as liquid nutrient media does not provide the necessary isolation required for pure culture. Choice D is incorrect because isolating from single colonies on solid media allows for the pure culture of the defined microorganism.
Question 4 of 9
A 32 year old patient complains about heartburn and dull pain in the epigastrium that appear 2-3 hours after meal. Exacerbations happen in spring and in autumn. The patient has food intolerance of eggs and fish. Objectively: stomach palpation reveals painfulness in the gastroduodenal area. Electrophasoduodenoscopy revealed a 5 mm ulcer on the anterior wall of duodenum. Urease test is positive. What is the most probable leading mechanism of disease development?
Correct Answer: A
Rationale: The correct answer is A: Helicobacterial infection. This is the most probable leading mechanism of disease development in this case because the patient's symptoms, such as heartburn, epigastric pain, food intolerance, and presence of a duodenal ulcer with a positive urease test, are classic signs of Helicobacter pylori infection. This bacterium colonizes the stomach lining, leading to inflammation and ulcer formation. The exacerbations in spring and autumn could be due to seasonal variations in immune response. Choice B: Dietary allergy is incorrect because the symptoms and findings in the patient are more indicative of an infectious etiology rather than an allergic reaction to specific foods. Choice C: Autoantibody production is unlikely as there are no indications of an autoimmune process in this case. Choice D: Reduced prostaglandin synthesis is not the leading mechanism as the symptoms and findings are more consistent with an infectious cause rather than a deficiency in prostaglandin synthesis.
Question 5 of 9
After 4 months of treatment for tuberculosis the patient began complaining of toes and fingers numbness, sensation of creeps. He was diagnosed with polyneuritis. What antituberculous drug might have caused these complications?
Correct Answer: A
Rationale: The correct answer is A: Isoniazid. Isoniazid is known to cause peripheral neuropathy as a side effect, especially with prolonged use. It can lead to symptoms such as numbness, tingling, and weakness in the toes and fingers due to its neurotoxic effects. Rifampicin (B) is less likely to cause neuropathy. Ciprofloxacin (C) is not typically associated with neuropathy. Sodium salt of benzylpenicillin (D) is an antibiotic but is not known to cause polyneuritis.
Question 6 of 9
A patient with severe pneumonia had a sputum culture revealing Gram-negative rods that are non-lactose fermenters. What is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. This is because Pseudomonas aeruginosa is a common Gram-negative rod that is a non-lactose fermenter and a common cause of severe pneumonia, especially in immunocompromised individuals. It is also known for its resistance to many antibiotics, making it difficult to treat. Summary of other choices: B: Escherichia coli is a lactose fermenter and is not commonly associated with severe pneumonia. C: Klebsiella pneumoniae is a lactose fermenter and is more commonly associated with pneumonia in alcoholics or debilitated patients. D: Enterobacter cloacae is a lactose fermenter and is not a common cause of severe pneumonia.
Question 7 of 9
Poxviruses are DNA viruses that replicate in the cytoplasm.
Correct Answer: A
Rationale: Step 1: Poxviruses are indeed DNA viruses, confirmed by scientific research. Step 2: Poxviruses replicate entirely in the cytoplasm, unlike most DNA viruses. Step 3: Cytoplasmic replication is a unique characteristic of poxviruses. Step 4: The replication process of poxviruses in the cytoplasm is well-documented. Step 5: Therefore, option A (TRUE) is correct, as poxviruses replicate in the cytoplasm exclusively.
Question 8 of 9
What type of bacteria is responsible for the formation of acid in the stomach?
Correct Answer: B
Rationale: The correct answer is B: Helicobacter pylori. This bacterium is responsible for stomach acid formation by producing an enzyme called urease, which converts urea into ammonia and carbon dioxide, leading to an increase in stomach pH. Staphylococcus aureus (A) does not cause stomach acid formation. Bacillus cereus (C) and Clostridium botulinum (D) are not involved in stomach acid processes.
Question 9 of 9
Examination of a smear from a chancre revealed mobile, long, spiral microorganisms with 8-12 regular coils. What is the causative agent?
Correct Answer: A
Rationale: The correct answer is A: Treponema. The characteristics described match Treponema pallidum, the causative agent of syphilis. Treponema has long, spiral shape with 8-12 regular coils. Leptospira (B) is a spirochete but has fewer coils and causes leptospirosis. Borrelia (C) is another spirochete but typically has irregular coils and causes Lyme disease. Vibrios (D) are curved rods and not spirochetes.