ATI RN
NCLEX Pediatric Immunization Questions Questions
Question 1 of 5
What structural feature is uniquely found on IgA in breast milk and not found on serum IgM?
Correct Answer: D
Rationale: The secretory piece (or secretory component) is unique to secretory IgA, such as that found in breast milk, and protects it from degradation in mucosal environments. Serum IgM lacks this feature.
Question 2 of 5
Rhesus D hemolytic disease of the newborn is classified as...?
Correct Answer: B
Rationale: Rhesus D hemolytic disease is a Type II hypersensitivity reaction, involving antibody-mediated destruction of red blood cells.
Question 3 of 5
Type II Hypersensitivity...?
Correct Answer: B
Rationale: Type II hypersensitivity involves antibodies binding to cell surface antigens, leading to complement-mediated or phagocytic destruction.
Question 4 of 5
A 5-year-old boy presents with his third episode of painful cervical lymphadenitis. Each was treated with incision and drainage and grew Staphylococcus aureus. At the age of 2 years, he required surgical aspiration of a liver abscess. The most important laboratory test is
Correct Answer: B
Rationale: The nitroblue tetrazolium (NBT) test assesses the ability of neutrophils to produce a respiratory burst, which is defective in chronic granulomatous disease (CGD). The history of recurrent Staphylococcus aureus infections and a liver abscess strongly suggests CGD, making the NBT test the most important diagnostic tool.
Question 5 of 5
Matching: Immunodeficiency - Splenomegaly
Correct Answer: C
Rationale: Common variable immunodeficiency (CVID) often presents with splenomegaly due to lymphoid hyperplasia or chronic infections. Bruton and Hyper IgM can also have splenomegaly, but CVID is more commonly associated.