What serious adverse reaction can occur with the loop diuretic Furosemide?

Correct Answer: A

Rationale: Furosemide, a loop diuretic, can rarely lead to a serious adverse reaction known as Stevens-Johnson syndrome. Stevens-Johnson syndrome is a severe skin reaction that can be life-threatening and typically involves painful blistering and shedding of the skin. This reaction is considered a serious medical emergency and requires immediate medical attention. It is crucial to monitor for any signs of skin changes or reactions while using Furosemide and report them to a healthcare provider promptly.

Correct Answer: B

Rationale: Lithium is primarily used in the treatment of bipolar disorder to decrease the incidence of acute manic episodes. It helps to stabilize mood and prevent the extreme highs (manic episodes) associated with bipolar disorder. Lithium is not used to decrease blood pressure, seizure activity, or increase urinary output.

Correct Answer: B

Rationale: Naloxone is the appropriate medication to be administered to a patient with a suspected opioid overdose. Naloxone is an opioid receptor antagonist, meaning it can quickly reverse the effects of opioids on the central nervous system. It works by binding to the same receptors in the brain that opioids target, blocking their effects and rapidly restoring normal respiration and consciousness in a person who has overdosed on opioids. This can be a life-saving treatment for opioid overdose patients. Exenatide, Heparin, and Tolvaptan are not appropriate medications for reversing opioid overdose.

Correct Answer: C

Rationale: The therapeutic range for Lithium is typically considered to be 0.6-1.2 mEq/L for maintenance treatment. However, some sources may also suggest a wider therapeutic range of 0.5-2 mEq/L. Monitoring serum lithium levels is crucial to ensure that the patient is within the therapeutic range and to adjust the dosage accordingly to avoid toxicity or subtherapeutic levels. Thus, option C (0.5-2) provides a more comprehensive and inclusive range that is commonly referenced in clinical practice.

Correct Answer: B

Rationale: EMLA (Eutectic Mixture of Local Anesthetics) is a commonly used topical local anesthetic cream. It contains a combination of lidocaine and prilocaine. This combination of local anesthetics work together to provide effective pain relief when applied to the skin before certain medical procedures like needle insertion, laser treatment, or minor skin surgeries. Lidocaine and prilocaine work by blocking nerve signals in the skin, reducing sensations of pain and discomfort in the area where the cream is applied.