ATI RN
Basic Principles of Pharmacology Quizlet Questions
Question 1 of 5
What percentage of the drug valproic acid is most likely lipid soluble in the patient's duodenal lumen?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Which of the following factors regulates the relationship between drug concentration and drug-receptor complex formation?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following conditions most likely delayed the oral absorption of acetaminophen in the patient who took a large dose in aqueous solution?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
A new drug was tested in an in vitro system. It was found that only one enantiomer of the racemic pair bound substantially to a specific receptor, whereas the other enantiomer showed negligible binding. Which of the following terms best defines this property?
Correct Answer: A
Rationale: Stereoselectivity refers to the phenomenon where one enantiomer of a racemic pair exhibits a significantly different interaction compared to the other enantiomer. In this case, the enantiomer that binds substantially to the receptor while the other does not demonstrates stereoselectivity. The term "intrinsic activity" refers to the ability of a drug to activate a receptor, "affinity" refers to the strength of binding between a drug and its receptor, and "potency" refers to the concentration of a drug required to produce a specific effect. Therefore, the correct answer is A.
Question 5 of 5
What was most likely the immediate consequence of the activation of beta receptors in the 9-year-old boy suffering from mild asthma?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.