What part of a neuron receives the signal?

Correct Answer: C

Rationale: The correct answer is C: Dendrites. Dendrites are the part of the neuron that receives signals from other neurons. They contain receptors that can detect neurotransmitters released by neighboring neurons. The signal is then transmitted through the cell body (soma) and along the axon to the axon terminals for further communication. Incorrect choices: A: Axon - The axon is responsible for transmitting the signal away from the cell body. B: Axon Terminal - The axon terminal releases neurotransmitters to communicate with the next neuron. D: Soma - The soma (cell body) integrates incoming signals but does not directly receive the signal from other neurons.

Correct Answer: D

Rationale: Carbamazepine is an enzyme inducer, specifically of CYP3A4 and CYP2C enzymes. It increases the metabolism of drugs metabolized by these enzymes, leading to decreased drug levels and potential therapeutic failure. Quinidine, Ketoconazole, and Amiodarone are not enzyme inducers, but rather enzyme inhibitors, which can increase drug levels and lead to toxicity.

Correct Answer: D

Rationale: The correct answer is D: GABA. GABA (Gamma-aminobutyric acid) is considered the chief inhibitory neurotransmitter in the central nervous system. It works by reducing the activity of neurons, leading to a calming or inhibitory effect. Serotonin (A) and histamine (B) are involved in mood regulation and wakefulness, respectively, but they are not primarily inhibitory. Glutamate (C) is the primary excitatory neurotransmitter in the brain, enhancing neuronal activity rather than inhibiting it.

Correct Answer: D

Rationale: The correct answer is D, the Mesocortical pathway. This pathway is responsible for cognitive functions and emotional responses. Decreased dopamine levels in the Mesocortical pathway lead to negative symptoms of schizophrenia such as cognitive deficits and flattened affect. The other pathways (A, B, C) are not associated with negative symptoms of schizophrenia. A: Nigrostriatal pathway is linked to motor control; B: Tuberoinfundibular pathway is involved in regulating prolactin release; C: Mesolimbic pathway is associated with positive symptoms of schizophrenia. Therefore, D is the correct choice based on the role of the Mesocortical pathway in producing negative symptoms of schizophrenia.

Correct Answer: D

Rationale: The correct answer is D because ziprasidone is associated with QT prolongation, which can lead to serious cardiac issues like myocardial infarction and heart failure. This contraindication is crucial to prevent life-threatening complications. Choices A and B are incorrect as they are not specific contraindications for ziprasidone. Choice C is also incorrect as liver disease is not a major contraindication for ziprasidone. Hence, option D is the correct answer due to its direct link to cardiac risks associated with ziprasidone use.