ATI RN
Cardiovascular System Drugs Questions
Question 1 of 5
What molecular action likely mediated the therapeutic effect of acetazolamide in the 56-year-old woman with congestive heart failure?
Correct Answer: A
Rationale: The correct answer is A: Inhibition of carbonic acid dehydration in the tubular lumen. Acetazolamide inhibits the enzyme carbonic anhydrase in the proximal convoluted tubule of the kidney, leading to decreased reabsorption of bicarbonate ions and subsequent loss of bicarbonate in the urine. This results in a metabolic acidosis which can help alleviate symptoms of congestive heart failure by reducing the workload on the heart. Choice B is incorrect because acetazolamide actually leads to increased bicarbonate excretion, not reabsorption. Choice C is incorrect because acetazolamide does not directly affect Na+ reabsorption in the distal tubule. Choice D is incorrect because acetazolamide does not stimulate H+ reabsorption in the proximal tubule; rather, it inhibits carbonic acid dehydration.
Question 2 of 5
During Phase 2 of action potential in cardiac cell, depolarizing current through calcium channels is balanced by
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following would least likely benefit a patient in acute pulmonary edema due to congestive heart failure?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
The nurse is given an order to give the client milrinone (Primacor). For what reason might this drug be ordered?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
The client is experiencing a drug-drug reaction by taking aspirin with what other drug?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.