ATI RN
Quizlet Pharmacology ATI Questions
Question 1 of 5
What medication, if ordered for an 8-year-old patient, should the nurse question? (Select all that apply.)
Correct Answer: A
Rationale: Amiodarone, labetalol, and carvedilol are not indicated for pediatric use and do not have established pediatric dosages. Phentolamine and prazosin have established pediatric dosages and would not need to be questioned. The nurse should always verify the appropriateness of medications for pediatric patients, as their pharmacokinetics and pharmacodynamics differ from adults.
Question 2 of 5
A pregnant patient who is at 32 weeks' gestation has a cold and calls the office to ask about taking an over-the-counter medication that is rated as pregnancy category A. Which answer by the nurse is correct?
Correct Answer: D
Rationale: Pregnancy category A indicates that adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus. Therefore, the nurse can reassure the patient that the medication is safe to take as directed. The other options either overstate the risk or provide incomplete information. It is important for the nurse to provide accurate and evidence-based guidance to ensure the safety of both the patient and the fetus.
Question 3 of 5
A female patient needs a whole blood transfusion. In order for transfusion services (the blood bank) to prepare the correct product a sample of the patient's blood must be obtained for:
Correct Answer: B
Rationale: A blood type and crossmatch are essential before a whole blood transfusion to ensure compatibility between the donor and recipient. This process involves determining the patient's blood type (ABO and Rh) and testing for antibodies that could cause a transfusion reaction. A complete blood count and differential are not required for transfusion preparation. Blood culture and sensitivity are used to diagnose infections, not for transfusion compatibility. Therefore, blood type and crossmatch are the correct steps.
Question 4 of 5
Which of the following drugs blocks reuptake of 5-hydroxytryptamine (serotonin)?
Correct Answer: D
Rationale: Serotonin reuptake blockade increases synaptic levels. Buspirone, a 5-HT1A agonist, treats anxiety without reuptake effects. Pizotifen, a serotonin antagonist, prevents migraines. Granisetron, a 5-HT3 antagonist, controls nausea. Paroxetine, an SSRI, potently inhibits serotonin reuptake, elevating mood in depression. Sumatriptan activates 5-HT1 receptors. Paroxetine's mechanism is central to its antidepressant efficacy, distinguishing it from receptor modulators.
Question 5 of 5
Regarding biotransformation, which of the following is true:
Correct Answer: B
Rationale: Ethanol competes with methanol metabolism, not enhances it, increasing toxicity, so that's false. Grapefruit juice inhibits CYP3A4, reducing cyclosporin metabolism, raising levels, a true statement critical for transplant patients. Phenytoin induces, not inhibits, theophylline metabolism, lowering levels. Rifampicin induces, not inhibits, oral contraceptive metabolism, reducing efficacy. Griseofulvin induces warfarin metabolism, not inhibits. Grapefruit juice's effect is a classic drug-food interaction, necessitating dose adjustments or avoidance.