ATI RN
Safety Pharmacology Across the Lifespan Questions
Question 1 of 5
What makes Losartan different from other ARBs?
Correct Answer: C
Rationale: Losartan is different from other ARBs because it undergoes hepatic metabolism to form an active metabolite, which contributes significantly to its pharmacological effects. This active metabolite, known as E-3174, has a longer half-life compared to Losartan itself, making its duration of action more sustained. Choices A, B, and D are incorrect because Losartan does not have the shortest half-life, does not have a small volume of distribution, and is primarily metabolized by the liver rather than being renally eliminated.
Question 2 of 5
Your patient is allergic to penicillin and sulfa medications. Which antibiotic can be given safely to the patient?
Correct Answer: C
Rationale: Step 1: Patient allergic to penicillin and sulfa, ruling out choices A, B, and D which contain cephalosporins. Step 2: Zithromycin (Choice C) is a macrolide antibiotic, unrelated to penicillin or sulfa, making it safe for the patient. Summary: A, B, and D are incorrect due to containing cephalosporins, which can cross-react with penicillin allergy. Choice C (Zithromycin) is the correct answer as it is a safe alternative for the patient with penicillin and sulfa allergies.
Question 3 of 5
A 17 year old asthmatic patient has been told that marijuana may help with his anxiety. Which adverse effect has been associated with marijuana and may be a reason for this patient to avoid use of marijuana?
Correct Answer: A
Rationale: The correct answer is A: Short term memory loss. Marijuana has been associated with impairing short-term memory due to its effects on the brain's hippocampus. This may be concerning for the 17-year-old asthmatic patient as it can affect cognitive function, learning, and overall daily functioning. Other choices are incorrect: B: Hepatitis is not directly associated with marijuana use. C: Hyperthermia is more commonly linked to stimulant drug use rather than marijuana. D: Hyponatremia is not a well-known adverse effect of marijuana.
Question 4 of 5
Which prescriber action will have the greatest impact on the patient's commitment to adherence to any type of medication therapy?
Correct Answer: D
Rationale: The correct answer is D because providing medication education that the patient can easily understand will empower the patient with knowledge about their medication, leading to better understanding, motivation, and commitment to adherence. This action promotes patient engagement and self-efficacy, enhancing their ability to follow the prescribed therapy. Choice A is incorrect because insurance coverage does not directly impact a patient's commitment to adherence. Choice B is less impactful as the form of medication may not significantly influence adherence compared to education. Choice C, while beneficial in simplifying the regimen, does not address the underlying factors affecting adherence like understanding.
Question 5 of 5
For his asthma, a patient is prescribed albuterol in the form of an inhalant. The patient tells you the medication causes shakes and hand tremors. What is the best response?
Correct Answer: B
Rationale: Rationale: Choice B is correct because tremors are a known common side effect of albuterol inhalant, usually temporary. This response reassures the patient and provides accurate information. Choice A is unnecessary as tremors are a common side effect, not requiring immediate intervention. Choice C is incorrect as the tremors are likely related to the medication. Choice D is not the best response as the patient's concern can be addressed by explaining the common side effect and its temporary nature.