What is the therapeutic range for lithium?

Questions 31

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Pharmacology ATI Proctored Exam 2024 Questions

Question 1 of 5

What is the therapeutic range for lithium?

Correct Answer: D

Rationale: The therapeutic range for lithium is generally considered to be 0.6-1.2 mmol/L (which is equivalent to 0.6-1.2 mEq/L). However, some sources may state a slightly wider range of 0.5-1.5 mEq/L. It is important to note that individual patient factors and clinical judgment should also be considered when interpreting lithium levels. Levels below the therapeutic range may be subtherapeutic and not provide the desired therapeutic effect, while levels above the range may result in toxicity and adverse effects. Monitoring lithium levels regularly is important to ensure they remain within the therapeutic range.

Question 2 of 5

Centrally acting antitussives, such as opioids, are used to

Correct Answer: C

Rationale: Opioid antitussives suppress severe coughs , not congestion , mucus , or mild coughs . C reflects their use, making it correct.

Question 3 of 5

A patient is concerned about the adverse effects of the fibric acid derivative she is taking to lower her cholesterol level. Which is an adverse effect of this class of medication?

Correct Answer: C

Rationale: Adverse effects of fibric acid derivatives, also known as fibrates, may include joint pain among other side effects such as gastrointestinal symptoms, abnormalities in liver function tests, and myopathy (muscle damage). Joint pain can be a result of musculoskeletal side effects associated with fibrates, so it is important for the patient to report any new or worsening joint pain to their healthcare provider.

Question 4 of 5

A 35-year-old African American male in the military is hospitalized with an MRSA skin infection. The patient starts treatment with an antibiotic and becomes anemic and jaundiced. On peripheral blood smear, Heinz bodies are seen within red blood cells. What is the mechanism of action of the antibiotic given to this patient?

Correct Answer: D

Rationale: MRSA treatment causing anemia, jaundice, and Heinz bodies suggests dapsone (sulfa drug), which inhibits folic acid metabolism . Oxidative stress from dapsone in G6PD-deficient patients (common in African Americans) leads to hemolysis. Options and are macrolide and tetracycline mechanisms. Option is penicillin's action. RNA polymerase inhibition (E) is rifampin's. Dapsone's sulfa action fits the clinical picture, with hemolysis as a side effect, not its primary MRSA mechanism, but the question's focus on outcome aligns with folate pathway disruption.

Question 5 of 5

Phenobarbital (luminal) is given to a client for a short treatment of anxiety. Which of the following results would indicate a therapeutic serum range of the medication?

Correct Answer: A

Rationale: The therapeutic serum range for phenobarbital (luminal) when used for anxiety is typically between 5-10 mcg/ml. This range is considered effective in controlling anxiety symptoms while minimizing the risk of toxicity. Higher serum levels (options B, C, D) may increase the risk of adverse effects such as sedation, respiratory depression, and overdose. Therefore, monitoring the serum levels of phenobarbital is essential to ensure the medication is at a therapeutic range for the intended treatment.

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