What is the therapeutic range for lithium?

Correct Answer: D

Rationale: The therapeutic range for lithium is generally considered to be 0.6-1.2 mmol/L (which is equivalent to 0.6-1.2 mEq/L). However, some sources may state a slightly wider range of 0.5-1.5 mEq/L. It is important to note that individual patient factors and clinical judgment should also be considered when interpreting lithium levels. Levels below the therapeutic range may be subtherapeutic and not provide the desired therapeutic effect, while levels above the range may result in toxicity and adverse effects. Monitoring lithium levels regularly is important to ensure they remain within the therapeutic range.

Correct Answer: B

Rationale: Idiosyncratic reactions to drugs refer to individual responses that cannot be explained by known mechanisms or understood pharmacological properties of the drug. These reactions are typically unpredictable and uncommon. Unlike allergic reactions that involve a specific immune response, idiosyncratic reactions are unique to the individual and may not be fully understood. Side effects, on the other hand, are known and expected effects of a drug, while teratogenic effects are related to drug exposure during pregnancy causing harm to the fetus.

Correct Answer: D

Rationale: The diagnostic triad of morphine overdose includes coma, depressed respiration, and pinpoint pupils. Coma occurs due to the central nervous system depression caused by morphine. Depressed respiration is a common symptom of opioid overdose, leading to respiratory distress and potential respiratory failure. Pinpoint pupils, also known as miosis, are a classic sign of opioid overdose and result from the effect of morphine on the autonomic nervous system. These three symptoms together are characteristic of a morphine overdose and indicate a medical emergency that requires prompt treatment.

Correct Answer: D

Rationale: Prednisone is a corticosteroid medication that can cause side effects such as fluid retention, electrolyte imbalance, and increased blood pressure. On the other hand, high-dose aspirin, especially when taken for arthritis, can have blood-thinning effects that may also contribute to lowering blood pressure. Given these potential effects of both medications, the nurse should be vigilant for the development of hypotension in the patient. Monitoring for signs and symptoms of low blood pressure, such as dizziness, lightheadedness, and weakness, is crucial in this situation to ensure the patient's safety.

Correct Answer: B

Rationale: Adrenergic blocking agents prevent norepinephrine from being released from the adrenal medulla or from the nerve terminal from activating the receptor, which blocks sympathetic nervous system effects. Epinephrine, serotonin, and GABA are not associated with this process. Norepinephrine is the primary neurotransmitter targeted by these agents, as it plays a key role in the sympathetic nervous system's fight-or-flight response.