ATI RN
ATI Pharmacology Proctored Exam 2024 Quizlet Questions
Question 1 of 5
What is the Therapeutic Effects of Lithium?
Correct Answer: A
Rationale: Lithium is commonly used as a mood stabilizer in the treatment of bipolar disorder. One of its main therapeutic effects is its ability to prevent or decrease the incidence of acute manic episodes in individuals with bipolar disorder. Lithium can help stabilize mood swings and reduce the severity and frequency of manic episodes. By regulating neurotransmitter levels in the brain, lithium helps to balance mood and prevent the extreme highs associated with mania. It is an essential medication for managing bipolar disorder and is particularly effective in treating manic symptoms.
Question 2 of 5
This serves as an indication of time required for a dosing regimen to achieve a steady state concentration of drug in blood
Correct Answer: B
Rationale: The half-life is the time required for the concentration of a drug in the blood to decrease by 50%. It serves as an indication of the time required for a dosing regimen to achieve a steady state concentration of the drug in the blood. Understanding the half-life of a drug is crucial for determining the dosing interval needed to maintain therapeutic levels. Long half-lives require less frequent dosing to reach steady state, while short half-lives demand more frequent dosing to achieve the desired drug concentration in the blood over time.
Question 3 of 5
The patient has generalized anxiety disorder. He asks the nurse, 'Will I need medication for this? My neighbor is very nervous and he takes medication.' What is the best response by the nurse?
Correct Answer: D
Rationale: Medication for GAD (e.g., SSRIs) is warranted when anxiety disrupts daily function-quality of life-not universally or compared to others, a tailored approach. Meds as lifestyle is extreme. Initial meds then therapy assumes progression, not individual need. ‘Probably not' dismisses severity. Quality of life guides treatment, per guidelines.
Question 4 of 5
A patient who is taking clopidogrel (Plavix) and aspirin is preparing for orthopedic surgery. The nurse will consult with the surgeon and provide which instruction to the patient?
Correct Answer: A
Rationale: The correct instruction for the patient taking clopidogrel (Plavix) and aspirin prior to orthopedic surgery is to continue taking aspirin and stop taking clopidogrel 2 weeks before the surgery. This recommendation is based on the pharmacokinetics of clopidogrel, which has a longer duration of action and requires a longer timeframe for platelet function to return to baseline after discontinuation. Aspirin, on the other hand, has a shorter duration of action, and its antiplatelet effects diminish more rapidly once it is stopped. By continuing aspirin and stopping clopidogrel 2 weeks before surgery, the patient can minimize the risk of excessive bleeding during the surgical procedure while still maintaining some level of antiplatelet effect to prevent thrombotic events.
Question 5 of 5
The oral bioavailability of a drug:
Correct Answer: B
Rationale: Bioavailability quantifies the extent of systemic drug absorption after oral administration, often expressed as a ratio of oral AUC to intravenous AUC.