ATI RN
ATI Pharmacology Study Guide Questions
Question 1 of 5
What is the therapeutic classification of Metformin?
Correct Answer: D
Rationale: Metformin belongs to the therapeutic classification of antidiabetic agents. It is commonly used to treat type 2 diabetes by helping to control blood sugar levels. Metformin works by decreasing glucose production in the liver and improving insulin sensitivity in the body's tissues. This helps the body use insulin more effectively, leading to better blood sugar control.
Question 2 of 5
Which of the following is most suitable for migraine prophylaxis in an otherwise healthy 30-year-old woman?
Correct Answer: C
Rationale: Migraine prophylaxis reduces attack frequency. Ergotamine treats acute migraines, not prophylaxis, risking vasoconstriction. Paracetamol relieves pain but doesn't prevent migraines. Propranolol, a beta-blocker, reduces migraine frequency via vascular and CNS effects, proven effective and safe in healthy adults. Carbamazepine suits trigeminal neuralgia, not migraines. Sumatriptan is acute, not preventive. Propranolol's efficacy makes it first-line, balancing prevention and tolerability.
Question 3 of 5
When teaching a patient who is beginning antilipemic therapy about possible drug-food interactions, the nurse will discuss which food?
Correct Answer: B
Rationale: The nurse will discuss grapefruit juice when teaching a patient about possible drug-food interactions with antilipemic therapy. Grapefruit juice can inhibit the enzyme CYP3A4 in the liver, which can affect the metabolism of certain medications, including some antilipemic drugs. This interaction may lead to increased drug levels in the bloodstream, potentially causing harmful side effects. It is important for patients to be aware of this interaction and to consult their healthcare provider if they consume grapefruit juice while on antilipemic therapy.
Question 4 of 5
A client with hyperlipidemia is prescribed simvastatin (Zocor). Which instruction should the nurse include?
Correct Answer: A
Rationale: Simvastatin, a statin, lowers cholesterol by inhibiting HMG-CoA reductase, most active at night when synthesis peaks. Evening dosing optimizes efficacy. Grapefruit juice increases levels, risking toxicity. Stopping if normal risks rebound. Breakfast misses the cycle. Evening aligns with simvastatin's pharmacodynamics, key in hyperlipidemia where timing boosts results, making A the key instruction.
Question 5 of 5
A client with bell's palsy tells the nurse that acetaminophen (Tylenol) is taken daily as prescribed by the physician. Which laboratory value would indicate a toxicity of the medication?
Correct Answer: A
Rationale: Acetaminophen (Tylenol) is primarily metabolized in the liver. Hepatotoxicity is a serious potential side effect of acetaminophen overdose or excessive use. One of the markers for liver damage due to acetaminophen toxicity is an elevated blood urea nitrogen (BUN) level. Normal BUN levels range from 7 to 20 mg/dl, and a level of 60 mg/dl indicates kidney dysfunction, which can result from liver damage caused by acetaminophen toxicity. Therefore, an elevated BUN level would indicate a toxicity of acetaminophen in this client with Bell's palsy who is taking acetaminophen daily. The other laboratory values mentioned are not specific markers for acetaminophen toxicity.