ATI RN
Immune System NCLEX Questions Questions 
            
        Question 1 of 5
What is the term for excessive lymph accumulation in tissues?
Correct Answer: D
Rationale: Lymphedema is lymph accumulation; lymphadenopathy is node swelling, lymphangitis is inflammation.
Question 2 of 5
Which cells release perforins to kill targets?
Correct Answer: B
Rationale: Cytotoxic T cells use perforins; NK cells also do, but B cells make antibodies, macrophages phagocytose.
Question 3 of 5
Which cells are key to the primary immune response?
Correct Answer: B
Rationale: Naïve lymphocytes respond first; memory is secondary, macrophages and neutrophils are innate.
Question 4 of 5
Which organ is central to adaptive immunity?
Correct Answer: C
Rationale: Lymph nodes activate adaptive responses; spleen filters, thymus matures T cells, marrow produces.
Question 5 of 5
With regard to secondary lymphatic nodules: They are characterised by a 'darkly basophilic central region'.
Correct Answer: A
Rationale: The germinal center stains darkly basophilic due to dense lymphocyte populations with heterochromatic nuclei.
