ATI RN
Lymphatic System Review Questions Questions
Question 1 of 5
What is the role of MHC molecules in organ transplant rejection?
Correct Answer: A
Rationale: Foreign MHC activates T cells to reject transplants ; they don't prevent attack and are central to rejection .
Question 2 of 5
Where would Peyer's patches be found?
Correct Answer: B
Rationale: Peyer's patches are in the small intestine , part of gut-associated lymphoid tissue (GALT).
Question 3 of 5
One surprising aspect of the immune system is that individuals make responses to human tissues from a different individual, causing serious problems for organ and tissue transplantation. The basis for this immune response is:
Correct Answer: A
Rationale: MHC polymorphism drives transplant rejection; microbes , blood groups , or APCs contribute less directly.
Question 4 of 5
NK cells express receptors from several families, each of which has multiple members. Some of these receptors are activating and others are inhibitory, and NK cell activation is dependent on the balance of signaling overall. The individual NK cells in an individual:
Correct Answer: C
Rationale: NK cells express a subset of receptors for balanced signaling; not always activating , not just cytotoxic , and are ILCs .
Question 5 of 5
The integrin LFA-1 is constitutively expressed on the surface of resting T cells. Yet, integrin-dependent T cell adhesion to antigen-presenting cells increases substantially following TCR stimulation. This increased integrin-dependent adhesion is mediated in part by:
Correct Answer: C
Rationale: TCR signaling shifts LFA-1 to high affinity ; not synthesis , transport , or just phosphorylation .