What is the role of macrophages in the innate immune system?

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Immune System Questions and Answers Quizlet Questions

Question 1 of 5

What is the role of macrophages in the innate immune system?

Correct Answer: C

Rationale: Macrophages engulf pathogens and fuse phagosomes with lysosomes to destroy them ; cytokine production and direct killing are secondary roles.

Question 2 of 5

Which cell produces IL-10 and TGFB to restrain the immune system?

Correct Answer: B

Rationale: iTreg cells produce IL-10 and TGF-β to suppress immunity ; CD8+ , NK , and neutrophils don't.

Question 3 of 5

Which of these is not a nonspecific defense against disease

Correct Answer: D

Rationale: Hair color and texture don't defend against disease; species resistance , phagocytosis , and interferon are nonspecific defenses.

Question 4 of 5

Unlike B lymphocytes, T lymphocytes do not generate a secreted form of their antigen receptor after they are activated and proliferate. This is because the effector functions of T cells are restricted to:

Correct Answer: C

Rationale: T cells interact with cells (e.g., infected or immune cells) via TCR ; not limited to protozoa , helminths , or mucosa .

Question 5 of 5

Most normal tissues contain resident macrophages, and connective tissue sites in the gastrointestinal tract and the lung contain large numbers of these cells. Yet the blood also contains a high number of circulating 'classical' monocytes that can differentiate into macrophages after entering tissues. These circulating monocytes function to:

Correct Answer: D

Rationale: Monocytes enter infected tissues to become macrophages ; blood phagocytosis , lining , or lymph node patrol are less primary.

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