What is the role of coagulase in bacteria like Staphylococcus aureus?

Correct Answer: C

Rationale: The correct answer is C because coagulase helps bacteria like Staphylococcus aureus to form clots, allowing them to evade the host immune response. This mechanism helps the bacteria to hide from the immune system and establish infection. A. Adhesion to surfaces is usually facilitated by other factors like adhesins. B. Breaking down red blood cells is not a function of coagulase. D. Antibiotic resistance is typically mediated by other mechanisms like efflux pumps or enzymatic inactivation, not coagulase.

Correct Answer: A

Rationale: The correct answer is A: Blood agar. Streptococcus pneumoniae is a fastidious bacterium that requires enriched media for growth. Blood agar provides the necessary nutrients and growth factors for the cultivation of S. pneumoniae, such as blood proteins and hemin. MacConkey agar (B) is selective for gram-negative bacteria and would not support the growth of S. pneumoniae. Peptone water (C) is a liquid medium that lacks the necessary nutrients for the growth of S. pneumoniae. Choice D is incorrect as blood agar is a suitable medium for cultivating S. pneumoniae.

Correct Answer: A

Rationale: The correct answer is A: Break down antibiotics like penicillin. Beta-lactamase is an enzyme produced by bacteria to inactivate beta-lactam antibiotics like penicillin by breaking the beta-lactam ring. This mechanism helps bacteria resist the antibiotic's effects. The other choices are incorrect because beta-lactamase does not enhance protein synthesis, facilitate DNA replication, or transport nutrients. It specifically targets and deactivates beta-lactam antibiotics, making choice A the most appropriate answer.

Correct Answer: C

Rationale: The correct answer is C: Candida albicans. Candida albicans is a common fungal organism that causes diaper rash in infants due to its ability to thrive in warm, moist environments. It can overgrow in the diaper area, leading to irritation and inflammation. Sporothrix schenckii (A) is a fungus that causes skin infections, but not typically diaper rash. Actinomyces (B) is a bacterium that is not commonly associated with diaper rash. Malassezia furfur (D) is a yeast that causes conditions like dandruff and seborrheic dermatitis, but not diaper rash in infants.

Correct Answer: D

Rationale: The correct answer is D: endemic. Endemic refers to a disease that is consistently present in a particular population or region at a relatively stable level. This means the disease is always present in that specific area. Pandemic (A) refers to a disease that spreads across multiple countries or continents. Epidemic (B) refers to a sudden increase in the number of cases of a disease above what is normally expected in that population. Sporadic (C) refers to occasional cases of a disease occurring irregularly in a population. Therefore, the correct choice is D as it specifically describes a disease that is generally present in a given population.

Correct Answer: A

Rationale: The correct answer is A: Yeast-like fungi of Candida genus. Candida is a common cause of oral thrush/stomatitis, characterized by mucosal lesions with white coating. The presence of large oval Gram-positive cells is indicative of Candida species. Actinomycetes (B) are filamentous bacteria and not oval Gram-positive cells. Streptococci (C) are spherical bacteria, not oval, and are not commonly associated with stomatitis. Oral spirochetes (D) are spiral-shaped bacteria and not oval Gram-positive cells typically seen in Candida infections. Thus, A is the correct choice based on the characteristic morphology and clinical presentation.

Correct Answer: A

Rationale: The correct answer is A: Entamoeba histolytica. This protozoan parasite causes amoebic dysentery and is characterized by cysts with four nuclei in fecal smears. It is commonly associated with chronic diarrhea. Balantidium coli (B) presents with large ciliated trophozoites, not cysts. Giardia lamblia (C) has trophozoites with flagella and causes giardiasis, not cysts with four nuclei. Trichomonas hominis (D) typically has a pear-shaped trophozoite and is not associated with cysts with four nuclei.

Correct Answer: A

Rationale: Peptidoglycan is a major component of bacterial cell walls, providing structural support and protection. The correct answer is A because peptidoglycan is typically found in the cell wall of bacteria. The cell wall is crucial for maintaining the shape of the bacterial cell and protecting it from external stresses. The plasma membrane (choice B) is primarily composed of phospholipids and proteins, not peptidoglycan. The nucleus (choice C) is found in eukaryotic cells and contains genetic material, not peptidoglycan. The endoplasmic reticulum (choice D) is an organelle involved in protein synthesis and lipid metabolism, but it does not contain peptidoglycan. Therefore, the correct answer is A as peptidoglycan is typically found in the cell wall of bacteria.

Correct Answer: A

Rationale: Step-by-step rationale for the correct answer (A - Clostridium tetani): 1. The patient has convulsive contractions of facial muscles, indicating tetanus. 2. Isolation of bacteria with terminal endospores that have a drumstick appearance is characteristic of Clostridium tetani. 3. Clostridium tetani produces tetanospasmin toxin causing muscle spasms. 4. Therefore, the correct answer is Clostridium tetani (A). Summary of why other choices are incorrect: B: Clostridium botulinum causes botulism, not tetanus. C: Clostridium perfringens causes gas gangrene, not tetanus. D: Bacillus anthracis causes anthrax, not tetanus.