What is the primary mechanism of action of methotrexate in rheumatoid arthritis?

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Question 1 of 5

What is the primary mechanism of action of methotrexate in rheumatoid arthritis?

Correct Answer: A

Rationale: Methotrexate primarily works by suppressing the immune system, reducing inflammation in rheumatoid arthritis.

Question 2 of 5

All the following are recognized in autistic spectrum disorder (ASD) EXCEPT

Correct Answer: D

Rationale: Truancy is not a recognized feature of ASD.

Question 3 of 5

A 15-year-old female presented with delusions, paranoia, tachycardia, hypertension, hyperpyrexia, diaphoresis, piloerection, mydriasis, hyperreflexia, seizures, hypotension, and dysrhythmia. The MOST likely cause is

Correct Answer: B

Rationale: Amphetamine intoxication matches these symptoms, including autonomic hyperactivity, psychosis, and cardiovascular effects.

Question 4 of 5

The patient described in Question 6 is most likely suffering from

Correct Answer: C

Rationale: Congenital pneumonia with sepsis is likely given the low WBC count, prematurity, and need for ventilation

Question 5 of 5

What is an anion gap?

Correct Answer: C

Rationale: The anion gap is calculated as (Na⁺ - [Cl⁻ + HCO₃⁻]) and represents unmeasured anions in plasma. It helps differentiate metabolic acidosis causes, with high values suggesting lactic acidosis or toxin ingestion.

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