What is the primary limitation of a case-control study?

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Question 1 of 5

What is the primary limitation of a case-control study?

Correct Answer: C

Rationale: Case-control studies (C) rely on memory, risking recall bias (e.g., cases recalling exposures differently). A, B, and D are less primary.

Question 2 of 5

Which type of study design is best suited for studying the natural history of a disease?

Correct Answer: C

Rationale: Cohort studies (C) follow disease progression (e.g., HIV). A is snapshot, B is retrospective, D is interventional.

Question 3 of 5

Which of the following can lead to information bias?

Correct Answer: A

Rationale: Information bias (A) includes misclassification (e.g., wrong exposure data). B and C are selection biases, D is confounding.

Question 4 of 5

The concept of 'minimal risk' in research ethics means:

Correct Answer: C

Rationale: Minimal risk (C) aligns with daily life risks (e.g., routine tests). A is vague, B is absolute, D is beneficence.

Question 5 of 5

If a diagnostic test has a sensitivity of 90% and a specificity of 95%, what does this imply?

Correct Answer: B

Rationale: Sensitivity 90% and specificity 95% (B) mean 90% of diseased and 95% of non-diseased are correctly identified. A is true but incomplete, C and D are false (5% FPR, 10% FNR).

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