ATI RN
Basic Immune System Quizlet Questions
Question 1 of 5
What is the primary effector cell in delayed-type hypersensitivity?
Correct Answer: B
Rationale: The primary effector cell in delayed-type hypersensitivity is T cells. T cells play a crucial role in initiating and orchestrating the immune response in delayed hypersensitivity reactions. Upon exposure to the antigen, T cells are activated and release cytokines that recruit and activate macrophages, leading to the inflammatory response characteristic of delayed-type hypersensitivity. Mast cells are involved in immediate hypersensitivity reactions mediated by IgE. Neutrophils are primarily involved in acute inflammation and combating bacterial infections. B cells are responsible for antibody production in humoral immunity, not in delayed hypersensitivity reactions. Therefore, the correct answer is B: T cells.
Question 2 of 5
A nurse caring for clients with systemic lupus erythematosus (SLE) plans care understanding the most common causes of death for these clients is which of the following? (Select one that does not apply.)
Correct Answer: C
Rationale: The correct answer is C: Vasculitis. Vasculitis is a common complication of systemic lupus erythematosus (SLE) and can lead to serious organ damage and even death. In SLE, inflammation affects blood vessels, leading to vasculitis which can cause tissue damage and impaired blood flow. While infections, cardiovascular impairment, and chronic kidney disease are also common causes of mortality in SLE patients, vasculitis is specifically associated with the disease and its complications. Infections can occur due to the immune system's weakened response, cardiovascular issues can arise from inflammation and damage to the heart and blood vessels, and chronic kidney disease can develop due to immune complex deposition in the kidneys. However, vasculitis is the most directly linked cause of death in SLE patients due to its impact on multiple organ systems.
Question 3 of 5
Which of the following molecular interactions mediate signal 2 during activation of naïve T cells
Correct Answer: E
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following is NOT true about multiple sclerosis (MS)
Correct Answer: A
Rationale: The correct answer is A: Sex bias observed with males more at risk of developing the disease. This statement is NOT true because MS actually has a sex bias towards females, with women being more at risk. This is due to hormonal, genetic, and immunological factors. The other choices are true: B is correct as MS is more common in northern regions, possibly due to environmental factors; C is correct since MS is characterized by demyelination of neurons leading to various symptoms; and D is correct as experimental autoimmune encephalomyelitis (EAE) is an animal model often used to study MS, induced by injecting myelin components to trigger an immune response.
Question 5 of 5
Which of the following is NOT true about a potential vaccine that induces a strong cytotoxic T cell response to influenza virus but failed to induce neutralizing antibodies:
Correct Answer: D
Rationale: The correct answer is D because a strong cytotoxic T cell response can still effectively clear the virus even without neutralizing antibodies. Cytotoxic T cells directly kill infected cells, helping to control and eliminate the virus. Therefore, the vaccine would not result in failure to clear the virus. A) Incorrect: While the vaccine may not prevent infection, the presence of cytotoxic T cells would help in controlling and reducing the severity of the infection. B) Incorrect: The vaccine may indeed lessen the severity of the disease by aiding in the clearance of infected cells. C) Incorrect: A strong T cell response can provide broader protection against different variants of the virus.