ATI RN
microbiology a systems approach test bank Questions
Question 1 of 9
What is the name of the enzyme that allows the bacteria to become resistant to most penicillins?
Correct Answer: C
Rationale: The correct answer is C: Beta lactamase. This enzyme is produced by bacteria to break down the beta-lactam ring structure of penicillins, rendering them ineffective. Beta lactam ring (A) is part of the penicillin molecule, not an enzyme. MRSA (B) stands for methicillin-resistant Staphylococcus aureus, a type of bacteria resistant to certain antibiotics, not an enzyme. Aminoglycoside ring (D) refers to a different class of antibiotics and is not related to penicillin resistance in bacteria.
Question 2 of 9
A patient complains of acute spastic abdominal pain, frequent urge to defecate, liquid bloody feces with mucus. Laboratory analysis of fecal smear revealed inconstant in shape organisms with erythrocyte. What is the most likely diagnosis?
Correct Answer: A
Rationale: The correct answer is A: Amebiasis. Amebiasis is caused by the parasite Entamoeba histolytica, presenting with symptoms like acute abdominal pain, bloody diarrhea with mucus, and inconstant shape organisms seen in fecal smear. The presence of erythrocytes supports the diagnosis due to the parasite's ability to invade intestinal mucosa causing bleeding. Choice B (Lambliasis) presents with different symptoms like steatorrhea and fatigue. Choice C (Schistosomiasis) is mainly associated with liver and urinary symptoms. Choice D (Intestinal trichomoniasis) commonly presents with watery diarrhea and does not typically cause bloody stools. Therefore, based on the patient's symptoms and fecal smear findings, Amebiasis is the most likely diagnosis.
Question 3 of 9
Which of the following bacterial structures has endotoxic activity?
Correct Answer: A
Rationale: The correct answer is A: Lipopolysaccharides. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria and are known to have endotoxic activity. LPS can trigger a strong immune response leading to inflammation and septic shock. Choice B, Lipoproteins of Braun, are not known to have endotoxic activity. Choice C, Protein A, is a surface protein found in Staphylococcus aureus and is not associated with endotoxic activity. Choice D, None, is incorrect as LPS is indeed a bacterial structure with endotoxic activity.
Question 4 of 9
Natural reservoirs of legionellae are:
Correct Answer: A
Rationale: The correct answer is A because Legionellae are typically found in natural water sources such as lakes, rivers, and soil. Legionellae thrive in aquatic environments and can also be present in mud. Choice B is incorrect as Legionellae are not limited to infected humans but are also found in the natural environment. Choice C is incorrect as Legionellae are not primarily associated with infected animals. Choice D is incorrect as Legionellae do have natural reservoirs in water and soil.
Question 5 of 9
What is the name of the enzyme that allows the bacteria to become resistant to most penicillins?
Correct Answer: C
Rationale: The correct answer is C: Beta lactamase. This enzyme is produced by bacteria to break down the beta-lactam ring structure of penicillins, rendering them ineffective. Beta lactam ring (A) is part of the penicillin molecule, not an enzyme. MRSA (B) stands for methicillin-resistant Staphylococcus aureus, a type of bacteria resistant to certain antibiotics, not an enzyme. Aminoglycoside ring (D) refers to a different class of antibiotics and is not related to penicillin resistance in bacteria.
Question 6 of 9
Antibiotics for multiple-resistant microorganisms are:
Correct Answer: D
Rationale: The correct answer is D: Imipenem. Imipenem is a carbapenem antibiotic effective against multiple-resistant microorganisms due to its broad spectrum and resistance to beta-lactamases. It is often used as a last resort for severe infections. Ampicillin (A) and Penicillin (B) are both beta-lactam antibiotics that are less effective against multiple-resistant microorganisms due to widespread resistance mechanisms. Augmentin (C) is a combination of amoxicillin and clavulanic acid, which may have limited efficacy against certain resistant strains but is not as effective as imipenem for treating infections caused by multiple-resistant microorganisms.
Question 7 of 9
Which bacteria is a common cause of urinary tract infections (UTIs)?
Correct Answer: B
Rationale: The correct answer is B: Escherichia coli. E. coli is the most common cause of UTIs due to its ability to colonize the urinary tract. It possesses adhesive factors that enable it to attach to the bladder and cause infection. Clostridium tetani causes tetanus, Mycobacterium leprae causes leprosy, and Bacillus anthracis causes anthrax, none of which are typically associated with UTIs. E. coli's prevalence in the gut and its pathogenic mechanisms make it the leading cause of UTIs.
Question 8 of 9
The following spore-forming bacteria can be preserved in soil over a long period of time: clostridia of tetanus, botulism, anaerobic gas infection. Name the way with which these microorganisms get into soil.
Correct Answer: A
Rationale: Step 1: Clostridia of tetanus, botulism, anaerobic gas infection are spore-forming bacteria. Step 2: Spores are resistant structures that allow bacteria to survive in harsh conditions. Step 3: Feces contain these spore-forming bacteria due to contamination. Step 4: When feces are deposited on soil, the spores of these bacteria enter the soil. Step 5: Spores can remain dormant in soil for long periods. Summary: Choice A is correct as spore-forming bacteria enter soil through feces, which act as a source of contamination. Choices B, C, and D are incorrect as they do not involve the direct introduction of spores into soil like feces do.
Question 9 of 9
A wound infection culture grew Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-negative. What is the likely microorganism?
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus epidermidis. The presence of Gram-positive cocci in clusters, along with being catalase-positive and coagulase-negative, is indicative of Staphylococcus species. Staphylococcus epidermidis is commonly found on the skin, making it likely to cause wound infections. Summary: B: Staphylococcus aureus is catalase-positive and coagulase-positive. C: Streptococcus pyogenes is catalase-negative. D: Enterococcus faecalis is catalase-negative.