Correct Answer: A

Rationale: The most appropriate amount for a weekly weight reduction goal is typically .5 to 1 pound per week. This rate of weight loss is considered safe and sustainable in the long term. Losing weight too quickly (options B, C, D) can be harmful to your health and may lead to muscle loss, nutritional deficiencies, and a slow metabolism. Rapid weight loss is also harder to maintain in the long run. Gradual weight loss of .5 to 1 pound per week allows for healthy changes to diet and exercise habits, making it more likely to be maintained over time. It is also more likely to result in lasting weight loss and overall improvements in health and well-being.

Correct Answer: C

Rationale: The presence of an irregular, asymmetric, hard nodule on the posterior surface of the prostate detected during digital rectal examination raises suspicion for prostate cancer. Prostate cancer commonly presents with nodules or indurations on the prostate gland during physical examination. Other findings, such as no inflammation, masses, or fissures in the anus and normal examinations of the scrotum and penis, further support the likelihood of prostate cancer as the most probable diagnosis in this case. Additional laboratory results, including prostate-specific antigen (PSA) levels, can help confirm the diagnosis. Both benign prostatic hyperplasia (BPH) and prostatitis typically present with different symptoms than those described in the scenario, making prostate cancer the most likely disorder based on the provided information. Anorectal cancer is less likely given the absence of findings indicating involvement of the anus or rectum in this case.

Correct Answer: B

Rationale: A sudden, painful unilateral loss of vision is a medical emergency that may be caused by central retinal artery occlusion. This condition occurs when the main artery supplying blood to the retina becomes blocked, leading to a sudden and severe reduction in blood flow to the eye. The lack of blood flow can cause irreversible damage to the retina, resulting in a significant loss of vision. Patients with central retinal artery occlusion typically present with sudden, painless, and severe vision loss in one eye. Immediate medical attention is crucial to try to restore blood flow and minimize potential permanent vision loss in these cases. Vitreous hemorrhage, macular degeneration, and optic neuritis do not typically present with sudden, painful unilateral loss of vision as seen in central retinal artery occlusion.

Correct Answer: A

Rationale: Intermittent claudication is a common symptom of peripheral vascular disease. It is characterized by muscle pain or cramping in the legs, usually in the calves, thighs, or buttocks, that occurs during physical activity such as walking and is relieved by rest. This symptom is due to inadequate blood flow to the muscles during exercise. It is important to assess for intermittent claudication in patients with risk factors such as smoking, diabetes, and hypertension, as it may indicate underlying peripheral arterial disease. The other symptoms listed (chest pressure with exertion, shortness of breath, knee pain) are not typically associated with peripheral vascular disease.

Correct Answer: C

Rationale: Shortness of breath is commonly associated with issues related to the heart and cardiovascular system. Conditions such as heart failure, coronary artery disease, or arrhythmias can lead to symptoms like shortness of breath. Therefore, the symptom of shortness of breath would be assigned to the cardiac anatomic region.