What is the major site for hematopoiesis, where all blood cells are formed?

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Pediatric Immunity NCLEX Questions Questions

Question 1 of 5

What is the major site for hematopoiesis, where all blood cells are formed?

Correct Answer: B

Rationale: Bone marrow is the primary site of hematopoiesis in adults.

Question 2 of 5

The spleen responds to antigens and the lymph nodes respond to antigens for presentation to

Correct Answer: D

Rationale: Spleen filters blood-borne antigens; lymph nodes process lymph-borne antigens for T cells.

Question 3 of 5

are trafficked via cell adhesion molecules (CAMs), which are a part of the immunoglobulin superfamily.

Correct Answer: C

Rationale: Both naïve and memory T cells use CAMs for trafficking.

Question 4 of 5

Which of the following best describes the role of the pre-B cell receptor (pre BCR)?

Correct Answer: A

Rationale: The pre-BCR signals proliferation and further development of pre-B cells.

Question 5 of 5

Most peripheral B cells belong to a pool of long lived follicular B lymphocytes called ___ cells. The majority of B cells found in the fetus and neonate are ___ cells, which express the surface marker CD5. ___ cells are the most likely to be involved in autoimmunity.

Correct Answer: B

Rationale: Peripheral B cells are predominantly B-2 (follicular B cells), while B-1 cells dominate in the fetus/neonate and express CD5. B-1 cells are implicated in autoimmunity due to their self-reactive nature.

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