What is the main site of distribution of infliximab, a drug used to treat rheumatoid arthritis?

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Principles of Pharmacology Questions

Question 1 of 4

What is the main site of distribution of infliximab, a drug used to treat rheumatoid arthritis?

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 4

Which of the following terms best defines the cimetidine-diazepam interaction in the 46-year-old woman?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 4

Which of the following is most likely the main site of distribution of infliximab?

Correct Answer: A

Rationale: Infliximab, as a monoclonal antibody, is a large molecule that is more likely to distribute to tissues like fat due to their ability to store and release drugs slowly. Fat tissue is a common site of distribution for large molecules and lipophilic drugs. Therefore, fat tissue is the most likely main site of distribution for infliximab.

Question 4 of 4

Which of the following factors regulates the relationship between drug concentration and drug-receptor complex association and dissociation?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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