What is the main role of neutrophils in the immune response?

Correct Answer: B

Rationale: Neutrophils play a crucial role in the immune response by engulfing and destroying pathogens through a process called phagocytosis. This is essential for eliminating harmful invaders from the body. Neutrophils do not produce antibodies (choice A), activate lymphocytes (choice C), or synthesize cytokines (choice D), which are functions typically carried out by other immune cells like B cells and macrophages. Therefore, the correct answer is B as it directly aligns with the primary function of neutrophils in the immune response, which is to combat infections by destroying pathogens.

Correct Answer: C

Rationale: The main function of the Membrane Attack Complex (MAC) is to lyse pathogens by creating pores in their cell membranes. First, MAC assembles on the pathogen's surface. Then, it forms a pore, disrupting the pathogen's membrane integrity, leading to cell lysis. This mechanism is crucial for the immune system to effectively eliminate pathogens. Choice A (Recruitment of neutrophils) is incorrect because MAC is not involved in recruiting neutrophils. Neutrophil recruitment is typically mediated by other signaling molecules. Choice B (Phagocytosis activation) is incorrect as MAC does not directly activate phagocytosis. Phagocytosis is a separate process involving the engulfment of pathogens by immune cells. Choice D (Enhancing cytokine production) is incorrect because MAC does not directly enhance cytokine production. Cytokine production is mainly regulated by other immune cells and signaling pathways.

Correct Answer: C

Rationale: The correct answer is C: 10. Toll-like receptors (TLRs) are a family of proteins involved in the innate immune response. In humans, there are 10 known TLRs that recognize different pathogen-associated molecular patterns. Each TLR is specific to different types of pathogens, allowing for a diverse recognition and response system. Therefore, the correct answer is 10. Choices A, B, and D are incorrect because they do not match the known number of TLRs in humans, which is 10.

Correct Answer: C

Rationale: Answer C is correct because B cell antibody production is part of adaptive immunity, not innate immunity. Innate immunity is the body's first line of defense and includes mechanisms like cytokine secretion, NK cell activity, and phagocytosis by macrophages. B cells are part of the adaptive immune response, producing antibodies specific to pathogens upon exposure. This distinction is crucial in understanding the different roles innate and adaptive immunity play in protecting the body.

Correct Answer: B

Rationale: Perforin released by NK cells forms pores in target cell membranes, allowing for the entry of granzymes which induce target cell death. This process is crucial for the immune response against infected or abnormal cells. Activating B cells (A) is not the role of perforin, as B cells are primarily activated by antigens. Engulfing pathogens (C) is the role of phagocytes like macrophages, not perforin. Inducing inflammation (D) is not directly related to the function of perforin in forming pores in target cell membranes.