ATI RN
Pediatric Immunization Practice Questions Questions
Question 1 of 5
What is the immunologic consequence of mutation in CD40L (CD154)?
Correct Answer: C
Rationale: CD40L mutation causes X-linked hyper-IgM syndrome, impairing class switching from IgM.
Question 2 of 5
Secrete cytokines if damaged
Correct Answer: D
Rationale: Living skin keratinocytes secrete cytokines when damaged as an innate response.
Question 3 of 5
Opsonization is the process by which bacteria and other cells are made available for phagocytosis and involves opsonin or IgG. Which complement components is/are mainly involved?
Correct Answer: B
Rationale: C3b is the primary opsonin in the complement system.
Question 4 of 5
Makes integrins more 'sticky'
Correct Answer: D
Rationale: Chemokines activate integrins to enhance adhesion.
Question 5 of 5
Parasitic worm eggs are resistant to low pH and proteolytic digestion in the stomach. Adult worms living inside the lower gut are protected from many of the components of the immune response. Mast cells respond to worms. What immunoglobulin activates these mast cells, leading to degranulation?
Correct Answer: C
Rationale: IgE is the key immunoglobulin involved in allergic and parasitic responses, binding to mast cells and triggering degranulation to combat worms.