ATI RN
Lymphatic System Quiz Questions Questions
Question 1 of 5
What is the highest state of macrophage activation called?
Correct Answer: C
Rationale: Hyperactivation is the highest macrophage activation state, beyond resting or basic activation ; MHC II upregulation is a feature, not a state.
Question 2 of 5
What is the role of natural regulatory T cells?
Correct Answer: B
Rationale: Natural Treg cells suppress self-reactive T cells ; they don't activate , target B cells , or cause hypermutation .
Question 3 of 5
Which of these does not belong with the others?
Correct Answer: A
Rationale: Thymus is a primary lymphoid organ; lymph node , sinus , and nodule are secondary lymphoid structures.
Question 4 of 5
Individuals with defects in T cell development have a severe immunodeficiency disease called SCID (severe combined immunodeficiency disease). In these individuals, the absence of all T cells causes defects in both cell-mediated (T cell-based) and humoral (antibody-based) immune responses. The defect in antibody responses in SCID patients is due to:
Correct Answer: D
Rationale: T follicular helper cells are critical for antibody responses; B-cell development is T-independent, organs form , phagocytes exist , B cells survive .
Question 5 of 5
Many different viruses encode proteins that function to down-regulate MHC class I expression on host cells following infection with the virus. This immune evasion mechanism allows the virus to hide from CD8 T lymphocytes that normally detect virus-infected cells by using their T cell antigen receptor to recognize viral peptides bound to MHC class I proteins on the surface of the infected cell. To counteract this immune evasion strategy, NK cells have:
Correct Answer: A
Rationale: NK cells use inhibitory MHC I receptors ; low MHC I activates them, not activating MHC or capsid (C/D) receptors.