ATI RN
ATI Capstone Pharmacology Assessment 2 Questions
Question 1 of 5
What is the antidote for Heparin?
Correct Answer: B
Rationale: Protamine is the antidote for Heparin. Heparin is an anticoagulant medication that prevents the formation of blood clots. In case of an overdose of Heparin or if there is a need to reverse its effects quickly (such as during surgery), Protamine is administered as the specific antidote. Protamine works by binding to Heparin and neutralizing its anticoagulant effects. Therefore, Protamine is the appropriate antidote to counteract the effects of Heparin.
Question 2 of 5
Select all the early manifestations of lithium
Correct Answer: A
Rationale: Nausea is one of the early manifestations of lithium toxicity. It is important to monitor for this symptom in patients taking lithium to detect toxicity early and prevent more serious complications. Hypotension and renal failure are more severe manifestations of lithium toxicity that occur at later stages. Muscle weakness is not typically associated with early lithium toxicity.
Question 3 of 5
Heparin:
Correct Answer: D
Rationale: Heparin is an anticoagulant that enhances the activity of antithrombin III, a natural inhibitor of thrombin and factor Xa, to prevent clotting. The statement that it inhibits clotting by decreasing antithrombin III effects is false, as heparin actually potentiates antithrombin III, making this the incorrect option. Its oral bioavailability is negligible (not 20-30%), as it's a large polysaccharide requiring parenteral administration (e.g., IV or subcutaneous), so this is false. Heparin is highly plasma protein-bound, not low, contradicting that option. The correct statement, replaced in the fourth slot, is that heparin binds to antithrombin III, causing a conformational change that accelerates its anticoagulant effect. This mechanism is fundamental to its clinical use in thrombosis prevention, distinguishing it from oral anticoagulants like warfarin.
Question 4 of 5
The nurse is monitoring for adverse effects in a patient who is receiving an amiodarone
Correct Answer: B
Rationale: - Tachycardia (increased heart rate) can be an adverse effect of amiodarone. This medication is used to treat irregular heartbeats, so it's important to monitor for any abnormal heart rhythms, including tachycardia.
Question 5 of 5
Which of the following describes the action of an agonist on a receptor.
Correct Answer: C
Rationale: An agonist is a substance that binds to a receptor and triggers a biological response. By activating the receptor, an agonist mimics the action of the body's natural ligand that typically binds to the receptor. This activation may lead to a cascade of events within the cell, resulting in a specific physiological response. In contrast, antagonists block the receptor from being activated, while agonists work by binding to the receptor and initiating the desired response.