What is the administration route of Ondansetron?

Correct Answer: D

Rationale: Ondansetron is typically administered orally, commonly in the form of tablets, orally disintegrating tablets, or liquid solution. The medication is absorbed through the gastrointestinal tract when taken orally, making it an effective route of administration for managing nausea and vomiting. SubQ (subcutaneous), sublingual, and buccal routes are not typical routes of administration for ondansetron.

Correct Answer: C

Rationale: Albuterol is a bronchodilator medication commonly used to treat bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD). Albuterol can be given in various forms, including extended-release tablets for oral use, inhalation solutions for nebulization, and oral syrups. However, albuterol is not typically administered intravenously because it can cause severe cardiovascular side effects, such as tachycardia and arrhythmias, when given directly into the bloodstream. For this reason, intravenous administration of albuterol is contraindicated in most cases and is not a common route of administration for this medication.

Correct Answer: A

Rationale: Amphetamine overdose causes sympathomimetic toxicity: elevated heart rate (HR) and blood pressure (BP) from catecholamine release, mydriasis via alpha-adrenergic stimulation, and CNS excitation—aggressiveness, paranoia, and hallucinations—due to dopamine and norepinephrine excess. Ethanol overdose typically depresses CNS, causing sedation, not excitation, despite possible tachycardia. Fentanyl, an opioid, leads to respiratory depression and miosis, opposite to these symptoms. Flunitrazepam, a benzodiazepine, sedates and lowers BP. Marijuana might cause paranoia but not this full sympathomimetic profile. Amphetamine's stimulant properties directly explain the cardiovascular, pupillary, and psychiatric symptoms, making it the most likely culprit in this acute presentation.

Correct Answer: D

Rationale: The 74-year-old professional golfer is likely experiencing Prinzmetal™s angina, also known as variant angina. This type of angina is characterized by episodes of chest pain that occur at rest or during minimal physical exertion. It is caused by a spasm in the coronary arteries, leading to a temporary reduction or cessation of blood flow to the heart muscle. The chest pain associated with Prinzmetal™s angina can be severe and is often relieved by sublingual nitroglycerin, as described by the golfer. Additionally, the fact that the pain occurs towards the end of his golfing games suggests that it may be triggered by stress or exertion, common triggers for coronary artery spasm in Prinzmetal's angina.

Correct Answer: A

Rationale: Graded dose-response curves plot individual response intensity to dose increases (e.g., pain relief), a pharmacodynamic tool. Population curves (e.g., ED50) suit groups, not individuals. Large or small groups aggregate data, missing individual nuance. Individual focus defines graded curves, key for tailoring therapy.