What is hypersensitivity in immunology?

Correct Answer: A

Rationale: Step-by-step rationale: 1. Hypersensitivity in immunology refers to an exaggerated or inappropriate immune response. 2. This excessive response can lead to tissue damage and various immune-mediated conditions. 3. Choice A accurately describes this concept. Summary: - Choice A is correct as it accurately defines hypersensitivity. - Choice B is incorrect as hypersensitivity involves an exaggerated immune response, not an inability to mount one. - Choice C is incorrect as hypersensitivity is not a low-level immune reaction. - Choice D is incorrect as hypersensitivity is not a mechanism for faster immune response, but rather an overreaction.

Correct Answer: D

Rationale: The correct answer is D: T cell apoptosis. Anaphylaxis is a severe allergic reaction that involves a rapid immune response. T cell apoptosis is not a typical symptom of anaphylaxis. Rationale: 1. A: Sudden drop in blood pressure is associated with anaphylaxis due to systemic vasodilation. 2. B: Massive edema is common in anaphylaxis due to increased vascular permeability. 3. C: Severe bronchoconstriction is a hallmark of anaphylaxis, leading to respiratory distress. 4. D: T cell apoptosis is not a characteristic feature of anaphylaxis. T cells play a role in adaptive immunity, not the immediate hypersensitivity reaction seen in anaphylaxis. Summary: T cell apoptosis is not typically associated with anaphylaxis, unlike the other symptoms listed which are common manifestations of this severe allergic reaction.

Correct Answer: B

Rationale: The primary effector cell in delayed-type hypersensitivity is T cells. T cells play a crucial role in initiating and orchestrating the immune response in delayed hypersensitivity reactions. Upon exposure to the antigen, T cells are activated and release cytokines that recruit and activate macrophages, leading to the inflammatory response characteristic of delayed-type hypersensitivity. Mast cells are involved in immediate hypersensitivity reactions mediated by IgE. Neutrophils are primarily involved in acute inflammation and combating bacterial infections. B cells are responsible for antibody production in humoral immunity, not in delayed hypersensitivity reactions. Therefore, the correct answer is B: T cells.

Correct Answer: D

Rationale: The correct answer is D because abruptly stopping prednisone can lead to adrenal insufficiency due to suppression of the body's natural cortisol production. Adrenal insufficiency can be life-threatening. Priority is given to this information to ensure the client's safety. Choice A is incorrect as jitteriness or nervousness are common side effects but not the priority. Choice B is incorrect as sodium and fluid retention are potential side effects but not as critical as avoiding adrenal insufficiency. Choice C is incorrect as fat redistribution is a long-term effect but not as immediate as the risk of adrenal insufficiency.

Correct Answer: C

Rationale: The correct answer is C: Vasculitis. Vasculitis is a common complication of systemic lupus erythematosus (SLE) and can lead to serious organ damage and even death. In SLE, inflammation affects blood vessels, leading to vasculitis which can cause tissue damage and impaired blood flow. While infections, cardiovascular impairment, and chronic kidney disease are also common causes of mortality in SLE patients, vasculitis is specifically associated with the disease and its complications. Infections can occur due to the immune system's weakened response, cardiovascular issues can arise from inflammation and damage to the heart and blood vessels, and chronic kidney disease can develop due to immune complex deposition in the kidneys. However, vasculitis is the most directly linked cause of death in SLE patients due to its impact on multiple organ systems.