What is a hallmark of Type IV hypersensitivity?

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Question 1 of 5

What is a hallmark of Type IV hypersensitivity?

Correct Answer: B

Rationale: The correct answer is B because Type IV hypersensitivity reactions are delayed and T cell-mediated. Upon exposure to an antigen, sensitized T cells, specifically CD4+ T cells, release cytokines that recruit and activate macrophages and other effector cells, leading to tissue damage. Choice A is incorrect because Type I hypersensitivity reactions are immediate and IgE-mediated. Choice C is incorrect because immune complex-mediated hypersensitivity reactions are typically associated with Type III hypersensitivity. Choice D is incorrect because histamine release by mast cells is characteristic of Type I hypersensitivity reactions, not Type IV.

Question 2 of 5

What chemical in poison ivy is responsible for triggering contact dermatitis?

Correct Answer: B

Rationale: The correct answer is B: Urushiol oil. Urushiol oil is the allergen in poison ivy that triggers contact dermatitis. When urushiol oil comes into contact with the skin, it can cause an allergic reaction leading to redness, itching, and inflammation. Histamine (choice A) is a compound released by the body in response to allergens but is not the specific chemical in poison ivy. Lipopolysaccharide (LPS) (choice C) is a component of the outer membrane of certain bacteria and not present in poison ivy. C3a (choice D) is a complement protein involved in the immune response but not related to poison ivy dermatitis.

Question 3 of 5

A client calls the clinic to report exposure to poison ivy and an itchy rash that is not helped with over-the-counter antihistamines. What response by the nurse is most appropriate?

Correct Answer: C

Rationale: The correct answer is C: "You should be seen in the clinic right away." This response is appropriate because poison ivy rashes can worsen and may require prescription medications like corticosteroids. Seeing a healthcare provider ensures proper diagnosis and treatment. A: "Antihistamines do not help poison ivy." - Incorrect, as antihistamines may provide some relief for itching but are not the primary treatment for poison ivy rashes. B: "There are different antihistamines to try." - Incorrect, as trying different antihistamines may not address the underlying issue of poison ivy exposure. D: "You will need to take some IV steroids." - Incorrect, as IV steroids are typically reserved for severe cases and should be prescribed by a healthcare provider after evaluation.

Question 4 of 5

Follicular dendritic cells

Correct Answer: E

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Which of the following statements is NOT true

Correct Answer: B

Rationale: The correct answer is B: During T cell differentiation, the decision to become a TH1 or a TH2 cell CD4+ is not a random event. This is because T cell differentiation into TH1 or TH2 cells is guided by specific signals from the environment, such as cytokines present during activation. TH1 cells are induced by IL-12 and IFN-gamma, while TH2 cells are induced by IL-4. This process is not random but rather a result of specific signaling cues. A: During T cell development, the decision to become a CD4 or a CD8 positive cell is not a random event. It is determined by interactions with thymic stromal cells and the T cell receptor. C: TH2 CD4+ cells do secrete IL-4, so this statement is true. D: IL-10 is not a TH2 polarizing cytokine; rather, it is known to have regulatory functions in immune responses.

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