What is a common side e昀昀ect of Albuterol?

Correct Answer: A

Rationale: A common side effect of Albuterol, a bronchodilator medication used to treat asthma and other respiratory conditions, is paradoxical bronchospasm. This paradoxical reaction leads to an unexpected constriction of the airways instead of the expected relaxation. It can result in increased breathing difficulties and chest tightness, requiring immediate medical attention. Other possible side effects of Albuterol include tremors, palpitations, headache, and nervousness, but paradoxical bronchospasm is notable due to its potential severity and the need for prompt intervention.

Correct Answer: C

Rationale: The relationship of the blood concentration attained with initial dosing and the dose of drug given is best described by the concept of steady state. Steady state refers to the point at which the rate of drug input (dose) equals the rate of drug elimination, resulting in consistent drug levels in the blood. Achieving steady state typically requires several half-lives of the drug, during which the drug concentration gradually increases with each dose until it stabilizes. The dose of the drug given will influence how quickly steady state is reached and at what concentration the drug will be maintained in the body. Factors such as bioavailability, half-life, volume of distribution, and clearance play important roles in determining the dosage needed to reach and maintain steady state drug levels in the body.

Correct Answer: C

Rationale: Warfarin is highly bioavailable (near 100%), so 90% is close and true. It doesn't inactivate vitamin K but inhibits vitamin K epoxide reductase, reducing clotting factor synthesis, making that false. It can paradoxically cause venous thrombosis (e.g., skin necrosis) early in therapy due to protein C depletion, a true statement. Initial loading is typically 5-10 mg, not 0.5 mg, so that's false. Metronidazole increases its effect via metabolism inhibition, not bactericidal action. The thrombosis risk is a rare but serious side effect, highlighting the need for bridging with heparin during initiation.

Correct Answer: B

Rationale: Finasteride (Proscar), a 5-alpha reductase inhibitor, reduces prostate size in benign prostatic hyperplasia (BPH) by blocking dihydrotestosterone (DHT) production, shrinking glandular tissue and easing urinary obstruction. Relaxing penile smooth muscle is the role of phosphodiesterase-5 inhibitors like sildenafil, not finasteride. It lowers DHT, not testosterone, and may even slightly increase circulating testosterone, but that's not its aim. Stimulating RNA synthesis relates to androgens' anabolic effects, not finasteride's mechanism. Shrinking the prostate is its core function, taking months to reduce symptoms, distinct from acute smooth muscle relaxation or hormonal boosts, aligning with BPH management goals.

Correct Answer: A

Rationale: Pregnancy limits medication safety. Acetaminophen is safe, used for pain with minimal fetal risk. Ciprofloxacin risks cartilage damage. Methotrexate and Valproic acid are teratogenic. Warfarin (E) causes fetal bleeding. Acetaminophen's profile suits her needs.