ATI RN
Drugs Affecting the Female Reproductive System Quizlet Exam Questions
Question 1 of 5
What does the term 'bioavailability' mean?
Correct Answer: B
Rationale: The correct answer is B: Fraction of an unchanged drug reaching the systemic circulation following any route of administration. Bioavailability refers to the proportion of an administered dose of unchanged drug that reaches the systemic circulation. This is crucial in determining the effectiveness of a drug. Option A is incorrect because bioavailability is not specifically related to the amount excreted in urine. Option C is incorrect as it refers to permeability through the blood-brain barrier, which is a different concept. Option D is incorrect as it pertains to plasma protein binding, which is not the same as bioavailability. In summary, bioavailability is about the amount of a drug that reaches systemic circulation intact, making option B the correct choice.
Question 2 of 5
All of the following statements related to the binding of drugs by plasma proteins are correct EXCEPT:
Correct Answer: D
Rationale: The correct answer is D because bound drug is not the pharmacologically active part of the drug. The active form of a drug is the unbound fraction that can exert its pharmacological effects. When a drug is bound to plasma proteins, it is unable to exert its pharmacological action until it becomes unbound. Choice A is true because bound drug cannot diffuse into tissues. Choice B is correct because binding to plasma proteins decreases the apparent volume of distribution. Choice C is also true as displacement of bound drug can lead to increased effects of the drug due to increased free drug concentration.
Question 3 of 5
If a drug is eliminated by first-order kinetics, what remains constant?
Correct Answer: B
Rationale: First-order kinetics means the rate of drug elimination is proportional to the drug concentration. Clearance (choice B) represents the volume of plasma cleared of the drug per unit time, which remains constant in first-order kinetics. The other choices are incorrect because: A: In first-order kinetics, the amount of drug eliminated per unit time decreases as drug concentration decreases. C: The elimination half-life is independent of dose in first-order kinetics. D: Complete elimination within two half-lives is a general rule but not specific to first-order kinetics.
Question 4 of 5
The nurse is teaching a pregnant client how to decrease the gastrointestinal distress she experiences with prenatal vitamins. Which instruction would the nurse provide?
Correct Answer: B
Rationale: The correct answer is B: Eat when she takes her vitamins. This is because taking prenatal vitamins on an empty stomach can lead to gastrointestinal distress. Eating food along with the vitamins can help reduce the chances of nausea and other digestive issues. Choice A is incorrect as taking vitamins between meals may worsen gastrointestinal distress. Choice C, drinking orange juice, is incorrect as the acidity of the juice may exacerbate the stomach issues. Choice D, drinking milk, is also incorrect as dairy products can sometimes aggravate gastrointestinal problems. Eating a small snack or meal when taking prenatal vitamins is the most effective way to reduce discomfort.
Question 5 of 5
A primigravida client, 8 gestational weeks, is at the prenatal clinic for her first examination with complaints of nausea and vomiting 'every morning.' Which comment made by the client would indicate the need for further instruction?
Correct Answer: D
Rationale: The correct answer is D because chamomile tea is not recommended during pregnancy due to its potential to cause uterine contractions. A: Ginger cookies can help with nausea. B: Eating dry crackers before getting up can alleviate morning sickness. C: Avoiding foods with strong smells may reduce nausea. Therefore, D is the only choice that could potentially harm the pregnancy.