ATI RN
First Aid Cardiovascular Drugs Quizlet Questions
Question 1 of 5
What does “affinity” mean?
Correct Answer: B
Rationale: The correct answer is B because "affinity" refers to how tightly a drug binds to a receptor. This is crucial for the drug to exert its pharmacological effect. A: Plasma protein binding is not specifically related to affinity but affects drug distribution. C: Inhibiting potency is different from affinity, which is about binding strength. D: Bioavailability is about drug absorption, not binding to receptors. Thus, B is the most appropriate choice.
Question 2 of 5
Which of the following cholinesterase inhibitors is irreversible?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Indicate the ganglion-blocking drug, which can be taken orally for the treatment of hypertension?
Correct Answer: A
Rationale: The correct answer is A: Mecamylamine. Mecamylamine is a ganglion-blocking drug that can be taken orally for hypertension. It blocks nicotinic acetylcholine receptors in autonomic ganglia, leading to decreased sympathetic tone and vasodilation, which helps reduce blood pressure. Scopolamine (B) is an anticholinergic drug used for motion sickness, trimethaphane (C) is a ganglion-blocking drug but not suitable for oral administration, and vecuronium (D) is a neuromuscular blocking agent used during surgery.
Question 4 of 5
Which of the following agents is an alfa1 alfa2 beta1 beta2 receptor agonist?
Correct Answer: C
Rationale: The correct answer is C: Epinephrine. Epinephrine is an alpha1, alpha2, beta1, and beta2 receptor agonist. It acts on all four types of adrenergic receptors, making it unique among the choices. Methoxamine is a selective alpha1 agonist (A). Albuterol is a beta2 agonist (B). Norepinephrine is an alpha1, alpha2, and beta1 agonist, but not a beta2 agonist (D). Therefore, only epinephrine fits the criteria of being an alpha1, alpha2, beta1, and beta2 receptor agonist.
Question 5 of 5
Which of the following drugs is useful in the treatment of pheochromocytoma?
Correct Answer: C
Rationale: The correct answer is C: Phentolamine. Phentolamine is an alpha-adrenergic antagonist that helps block the effects of excess catecholamines released by pheochromocytoma. It helps to control hypertension and other symptoms associated with pheochromocytoma. A: Phenylephrine is an alpha-1 adrenergic agonist, which would worsen hypertension in pheochromocytoma. B: Propranolol is a beta-blocker, which can lead to unopposed alpha-adrenergic effects and exacerbate hypertension in pheochromocytoma. D: Epinephrine is a catecholamine that would exacerbate symptoms in pheochromocytoma due to its stimulatory effects on alpha and beta adrenergic receptors.