What are the drug natural interactions for phenytoin?

Correct Answer: B

Rationale: St. John's Wort is known to interact with phenytoin, a drug commonly used to treat seizures. St. John's Wort can decrease the effectiveness of phenytoin by increasing its metabolism in the liver. This interaction can lead to lower levels of phenytoin in the bloodstream, potentially reducing its therapeutic effects and increasing the risk of seizure recurrence. It is important for individuals taking phenytoin to avoid using St. John's Wort to prevent this drug interaction.

Correct Answer: B

Rationale: Sedatives and hypnotics are drugs that act as depressants on the central nervous system. They slow down brain activity, leading to relaxation, drowsiness, and in higher doses, inducing sleep. These drugs are commonly used to reduce anxiety, promote sleep, or induce anesthesia. Therefore, the correct classification for sedatives and hypnotics is as depressants.

Correct Answer: D

Rationale: Bradykinin is not an eicosanoid. Eicosanoids are signaling molecules derived from arachidonic acid or other polyunsaturated fatty acids, including prostaglandins, prostacyclins, thromboxanes, and leukotrienes. Bradykinin, on the other hand, is a peptide that functions as a mediator of inflammation and pain by promoting vasodilation and increasing vascular permeability.

Correct Answer: D

Rationale: Low-molecular-weight heparin is commonly administered to postoperative patients to help prevent thrombus formation caused by slow venous blood flow. This medication works by inhibiting the formation of blood clots. It is considered safer and more effective than unfractionated heparin in preventing venous thromboembolism in surgical patients. Aspirin and clopidogrel are antiplatelet medications that are more commonly used for preventing arterial thrombosis rather than venous thrombosis. Alteplase is a thrombolytic medication used to dissolve existing blood clots, rather than prevent their formation.

Correct Answer: B

Rationale: Epidermal growth factor receptor (EGFR) inhibitors commonly cause skin-related side effects, such as rash, dryness, and paronychia (nail inflammation). These side effects can lead to tissue injury and discomfort, impacting the patient's quality of life. While bone marrow suppression and reduced platelet activity are concerns with other chemotherapies, they are less common with EGFR inhibitors. Alopecia is also less frequently associated with these drugs. The nurse should prioritize monitoring and managing skin-related side effects to prevent complications and ensure patient comfort.