What action is often recommended to help reduce tolerance to transdermal nitroglycerin therapy?

Correct Answer: A

Rationale: Omitting a dose of transdermal nitroglycerin therapy once a week is often recommended to help reduce tolerance. Tolerance to nitroglycerin can develop with continuous use, limiting its effectiveness. By omitting a dose once a week, you are essentially giving the body a break from the medication and preventing tolerance from developing. This strategy can help maintain the efficacy of the nitroglycerin therapy over time. It is important to follow the guidance of a healthcare provider when making any changes to the dosing regimen of nitroglycerin to ensure safety and effectiveness.

Correct Answer: D

Rationale: Acute interstitial nephritis is a rare but serious adverse reaction associated with omeprazole. It is characterized by inflammation of the kidney's interstitial tissue and can lead to kidney dysfunction. Symptoms may include fever, rash, eosinophilia, and impaired renal function. If left untreated, acute interstitial nephritis can progress to acute kidney injury and potentially be life-threatening. Therefore, it is essential to promptly recognize and manage this adverse reaction when taking omeprazole.

Correct Answer: C

Rationale: Physostigmine is the antidote for Atropine overdose. Atropine is an anticholinergic drug that blocks the action of acetylcholine. Physostigmine works by increasing the levels of acetylcholine in the body, counteracting the effects of Atropine. It can help reverse the side effects of Atropine overdose, such as dry mouth, tachycardia, and drowsiness. Flumazenil is the antidote for benzodiazepines, Naloxone is the antidote for opioids, and Protamine sulfate is the antidote for heparin.

Correct Answer: B

Rationale: The patient's first action should be to stop mowing and sit or lie down. Chest pain can be a symptom of a heart attack, and it is important for the patient to immediately rest and avoid physical strain. Continuing to mow the lawn could worsen the condition or lead to further complications. Sitting or lying down will help reduce the heart's workload and minimize the exertion on the body. If the chest pain continues or worsens, seeking medical help should be the next course of action.

Correct Answer: B

Rationale: Plasmin is an enzyme that is responsible for breaking down fibrin, a protein that forms blood clots. When an area of vessel needs to have its blood flow restored, such as after a clot has formed, plasmin is activated to dissolve the clot. By breaking down the fibrin mesh of the clot, plasmin helps restore normal blood flow in the affected vessel. Therefore, the restoration of blood flow results through the dissolution of clot by plasmin, making option B the correct answer.